SCHEMBL29029673

SCHEMBL29029673

CCOC(=O)C(CC)(C(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PIN1 Q13526 1/20 0.50
POLB P06746 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
ALDH1A1 P00352 3/20 0.46
NPC1 O15118 2/20 0.46
MAPT P10636 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
SRC P12931 1/20 0.46
RECQL P46063 1/20 0.44
MMP8 P22894 1/20 0.44
LMNA P02545 1/20 0.43
TSHR P16473 1/20 0.43
CES1 P23141 2/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
GAA P10253 2/20 0.42
RAB9A P51151 1/20 0.42
MAPK1 P28482 1/20 0.41
ATM Q13315 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28332040 0.92 POLB (0.47) PIN1POLBNPSR1ALDH1A1NPC1
SCHEMBL27714041 0.83 CES1 (0.52) ALDH1A1MAPTMEN1KMT2ASRC
SCHEMBL9437357 0.82 PIN1 (0.53) PIN1POLBNPSR1ALDH1A1NPC1
SCHEMBL8679766 0.81 PIN1 (0.51) PIN1POLBNPSR1ALDH1A1NPC1
SCHEMBL4621876 0.81 PIN1 (0.51) PIN1POLBNPSR1ALDH1A1NPC1
SCHEMBL9437333 0.81 MEN1 (0.51) PIN1POLBNPSR1ALDH1A1NPC1
SCHEMBL28458817 0.81 SRC (0.66) PIN1POLBNPSR1ALDH1A1NPC1
SCHEMBL8478731 0.80 KMT2A (0.43) PIN1POLBNPSR1ALDH1A1MAPT
SCHEMBL29029684 0.80 CES1 (0.48) ALDH1A1MAPTMEN1KMT2ASRC
SCHEMBL8675207 0.79 PIN1 (0.50) PIN1POLBNPSR1ALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116219085-B Synthetic tanning agent containing multifunctional structure and preparation method and application thereof 南京工业大学 2024-03-15 CN disclosed
CN-116219085-A Synthetic tanning agent containing multifunctional structure and preparation method and application thereof 南京工业大学 2023-06-06 CN disclosed