Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.31 |
| ▸ | CKS1B | P61024 | 1/20 | 0.30 |
| ▸ | SKP1 | P63208 | 1/20 | 0.30 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.30 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.30 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22519008 | 0.78 | CHRM1 (0.46) | SLC6A7GRM1GPR119CHRM1CHRM2 | |
| SCHEMBL25264632 | 0.75 | CHRM4 (0.48) | SLC6A7CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL24467723 | 0.74 | GPR119 (0.53) | GPR119CKS1BSKP1SKP2 | |
| SCHEMBL3548310 | 0.73 | SLC6A7 (0.39) | SLC6A7GPR119CHRM1CHRM2CHRM4 | |
| SCHEMBL25383375 | 0.71 | SLC6A7 (0.45) | SLC6A7CHRM4SLC6A9 | |
| SCHEMBL5444352 | 0.69 | OPRM1 (0.43) | — | |
| SCHEMBL6337270 | 0.68 | SLC6A7 (0.43) | SLC6A7GRM1CHRM1CHRM2CHRM4 | |
| SCHEMBL31713675 | 0.68 | GPR119 (0.48) | SLC6A7GPR119CHRM4SLC6A9 | |
| SCHEMBL1449587 | 0.68 | GPR119 (0.50) | SLC6A7GPR119CHRM4 | |
| SCHEMBL5222720 | 0.68 | HDAC1 (0.48) | SLC6A7CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157396-A | Pyridazinone derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| WO-2022111700-A1 | PYRIDAZINONE DERIVATIVES AND USE THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2022-06-02 | — | — | WO | disclosed |