Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 2/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29631768 | 0.82 | HSD11B1 (0.44) | TRPV1RBP4HSD11B1GAA | |
| SCHEMBL23705807 | 0.78 | CHRM2 (0.51) | CHRM2CHRM1CHRM3SLC6A9GAA | |
| SCHEMBL23706068 | 0.75 | RBP4 (0.43) | RBP4CHRM2CHRM1CHRM3HCRTR2 | |
| SCHEMBL24467799 | 0.75 | CYP1A2 (0.44) | TRPV1GAA | |
| SCHEMBL29029902 | 0.74 | DDB1 (0.45) | TRPV1GAA | |
| SCHEMBL4159672 | 0.70 | NR1H2 (0.43) | SLC6A9 | |
| SCHEMBL3201930 | 0.70 | HSD11B1 (0.52) | HSD11B1 | |
| SCHEMBL24467777 | 0.70 | EPHX2 (0.52) | TRPV1GAA | |
| SCHEMBL29631810 | 0.70 | EPHX2 (0.52) | TRPV1GAA | |
| SCHEMBL26924824 | 0.70 | GRM1 (0.37) | GRM1SLC6A9SLC6A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157396-A | Pyridazinone derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| WO-2022111700-A1 | PYRIDAZINONE DERIVATIVES AND USE THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2022-06-02 | — | — | WO | disclosed |