Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | PAK4 | O96013 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.50 |
| ▸ | CSF1R | P07333 | 1/20 | 0.50 |
| ▸ | RET | P07949 | 1/20 | 0.50 |
| ▸ | MET | P08581 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
| ▸ | PRKACA | P17612 | 1/20 | 0.50 |
| ▸ | FLT1 | P17948 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19280727 | 0.85 | GPR84 (0.58) | GPR84CDK5CHEK1AURKADAPK3 | |
| SCHEMBL25417105 | 0.79 | F7 (0.53) | GPR84NR4A2HTR2ATRPM8IDO1 | |
| SCHEMBL17598432 | 0.79 | GPR84 (0.51) | GPR84CDK5CHEK1AURKADAPK3 | |
| SCHEMBL2979894 | 0.75 | KDM4E (0.68) | GPR84GABRA1GABRB1GABRA3GABRB2 | |
| SCHEMBL27795085 | 0.75 | GABRA1 (0.64) | GPR84GABRA1GABRB1GABRA3GABRB2 | |
| SCHEMBL5254495 | 0.75 | CSNK2A1 (0.53) | GPR84CDK5CHEK1AURKADAPK3 | |
| SCHEMBL16018002 | 0.73 | KMT2A (0.47) | HSD17B10LMNAHPGDMEN1GAA | |
| SCHEMBL16459160 | 0.73 | CAMK2D (0.49) | GPR84CDK5AURKAJAK2PRKD3 | |
| SCHEMBL17598434 | 0.73 | GPR84 (0.46) | GPR84CDK5CHEK1AURKADAPK3 | |
| SCHEMBL22128417 | 0.73 | CYP2A6 (0.55) | GPR84CDK5JAK2PIM1PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116377457-A | Electrochemical synthesis method of halogenated quinoline-4 (1H) -ketone derivative | 桂林理工大学 | 2023-07-04 | — | — | CN | disclosed |