Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.45 |
| ▸ | ULK1 | O75385 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29030401 | 0.85 | LMNA (0.47) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL30493616 | 0.85 | LMNA (0.47) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL6538118 | 0.82 | KDR (0.56) | SMN1; SMN2NPSR1HSD17B10KMT2AMEN1 | |
| SCHEMBL3768771 | 0.80 | NPC1 (0.81) | SMN1; SMN2NPSR1HSD17B10KMT2AMEN1 | |
| SCHEMBL17744840 | 0.76 | SMN1; SMN2 (0.71) | SMN1; SMN2NPSR1HSD17B10KMT2AMEN1 | |
| SCHEMBL27880345 | 0.74 | RAB9A (0.64) | SMN1; SMN2NPSR1HSD17B10KMT2AMEN1 | |
| SCHEMBL31386679 | 0.74 | PTK2 (0.46) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL7235873 | 0.74 | TP53 (0.78) | SMN1; SMN2NPSR1HSD17B10KMT2AMEN1 | |
| SCHEMBL29513264 | 0.73 | HDAC1 (0.69) | SMN1; SMN2NPSR1HSD17B10KMT2AMEN1 | |
| SCHEMBL16444873 | 0.73 | HDAC1 (0.69) | SMN1; SMN2NPSR1HSD17B10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116410152-A | Small molecular compound for inhibiting ASCT2, derivative thereof and application thereof | 江苏征瑞医药科技有限公司 | 2023-07-11 | — | — | CN | disclosed |