Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30493616 | 1.00 | LMNA (0.47) | LMNAMEN1KMT2APOLBTDP1 | |
| SCHEMBL29030352 | 0.85 | SMN1; SMN2 (0.55) | MEN1KMT2ATDP1HDAC1PTGS1 | |
| SCHEMBL31386679 | 0.77 | PTK2 (0.46) | LMNAMEN1KMT2ATDP1HDAC1 | |
| SCHEMBL15649640 | 0.72 | NPC1 (0.47) | MEN1KMT2APOLBTDP1HDAC1 | |
| SCHEMBL16444808 | 0.71 | HDAC1 (0.65) | LMNAMEN1KMT2APOLBTDP1 | |
| SCHEMBL5846612 | 0.70 | GPR35 (0.53) | LMNAMEN1KMT2APTGS1NPC1 | |
| SCHEMBL17744864 | 0.70 | MEN1 (0.66) | LMNAMEN1KMT2APOLBTDP1 | |
| SCHEMBL27588670 | 0.70 | HDAC1 (0.63) | LMNAKMT2AHDAC1NPC1RAB9A | |
| SCHEMBL15649386 | 0.70 | DEGS1 (0.47) | NPC1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL17243871 | 0.70 | HDAC1 (0.45) | LMNAMEN1KMT2APOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116410152-B | Small molecular compound for inhibiting ASCT2, derivative thereof and application thereof | 江苏征瑞医药科技有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-116410152-A | Small molecular compound for inhibiting ASCT2, derivative thereof and application thereof | 江苏征瑞医药科技有限公司 | 2023-07-11 | — | — | CN | disclosed |