Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.56 |
| ▸ | ITGAV | P06756 | 20/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.55 |
| ▸ | ITGB5 | P18084 | 4/20 | 0.55 |
| ▸ | ITGB6 | P18564 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2905059 | 0.91 | ITGB3 (0.67) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL2962102 | 0.80 | ITGB3 (0.57) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL2899642 | 0.80 | ITGB3 (0.84) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL2902444 | 0.74 | ITGB3 (0.76) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL2921996 | 0.73 | ITGB3 (0.74) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL2907831 | 0.73 | ITGB3 (0.56) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7676381 | 0.72 | ITGAV (1.00) | ITGB3ITGAVITGB6 | |
| SCHEMBL6536413 | 0.72 | ITGAV (1.00) | ITGB3ITGAVITGB6 | |
| SCHEMBL7458588 | 0.72 | ITGAV (1.00) | ITGB3ITGAVITGB6 | |
| SCHEMBL4251938 | 0.71 | ITGB3 (1.00) | ITGB3ITGAVITGA2BITGB5ITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217569-A1 | ENANTIOSELECTIVE PROCESS FOR PREPARING A SUBSTITUTED ALKANOIC ACID | Janssen Pharmaceutica N.V. (BE) | 2010-08-18 | — | — | EP | claimed |
| WO-2009058314-A1 | ENANTIOSELECTIVE PROCESS FOR PREPARING A SUBSTITUTED ALKANOIC ACID | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-05-07 | — | — | WO | claimed |