Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.57 |
| ▸ | ITGAV | P06756 | 20/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.57 |
| ▸ | ITGB5 | P18084 | 12/20 | 0.51 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.51 |
| ▸ | ITGB6 | P18564 | 4/20 | 0.49 |
| ▸ | ITGB8 | P26012 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2951622 | 0.89 | ITGB3 (0.65) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL2903113 | 0.80 | ITGB3 (0.56) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL3691013 | 0.79 | ITGB3 (0.86) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL2905059 | 0.77 | ITGB3 (0.67) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL6421258 | 0.73 | ITGAV (0.83) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL6357539 | 0.73 | ITGAV (0.83) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL6422503 | 0.73 | ITGAV (0.83) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL2927647 | 0.73 | ITGB3 (1.00) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL2902444 | 0.71 | ITGB3 (0.76) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL2899739 | 0.71 | ITGB3 (0.72) | ITGB3ITGAVITGA2BITGB5ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217569-A1 | ENANTIOSELECTIVE PROCESS FOR PREPARING A SUBSTITUTED ALKANOIC ACID | Janssen Pharmaceutica N.V. (BE) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009058314-A1 | ENANTIOSELECTIVE PROCESS FOR PREPARING A SUBSTITUTED ALKANOIC ACID | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-05-07 | — | — | WO | disclosed |