Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.56 |
| ▸ | PARP1 | P09874 | 4/20 | 0.50 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.50 |
| ▸ | TNKS | O95271 | 3/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.50 |
| ▸ | PDE9A | O76083 | 1/20 | 0.49 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | ADK | P55263 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29639169 | 1.00 | PTGS2 (0.56) | PTGS2PARP1SERPINE1TNKSTNKS2 | |
| SCHEMBL29031885 | 0.97 | SERPINE1 (0.56) | PTGS2PARP1SERPINE1TNKSTNKS2 | |
| SCHEMBL30472330 | 0.97 | SERPINE1 (0.56) | PTGS2PARP1SERPINE1TNKSTNKS2 | |
| SCHEMBL29639174 | 0.85 | SERPINE1 (0.67) | PTGS2PARP1SERPINE1TNKSTNKS2 | |
| SCHEMBL29031883 | 0.85 | SERPINE1 (0.67) | PTGS2PARP1SERPINE1TNKSTNKS2 | |
| SCHEMBL31014307 | 0.83 | SERPINE1 (0.71) | PTGS2PARP1SERPINE1TNKSTNKS2 | |
| SCHEMBL29031884 | 0.83 | SERPINE1 (0.71) | PTGS2PARP1SERPINE1TNKSTNKS2 | |
| SCHEMBL30472337 | 0.83 | PTGS2 (0.55) | PTGS2PARP1SERPINE1TNKSTNKS2 | |
| SCHEMBL29639170 | 0.83 | SERPINE1 (0.71) | PTGS2PARP1SERPINE1TNKSTNKS2 | |
| SCHEMBL29031838 | 0.83 | PTGS2 (0.55) | PTGS2PARP1SERPINE1TNKSTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116396206-A | Isoindolinone compound and preparation method and application thereof | 五邑大学 | 2023-07-07 | — | — | CN | disclosed |