Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 3/20 | 0.71 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.55 |
| ▸ | TNKS | O95271 | 2/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.50 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.50 |
| ▸ | GUSB | P08236 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29031883 | 0.85 | SERPINE1 (0.67) | SERPINE1PTGS2TNKSTNKS2PARP1 | |
| SCHEMBL29639174 | 0.85 | SERPINE1 (0.67) | SERPINE1PTGS2TNKSTNKS2PARP1 | |
| SCHEMBL29031852 | 0.83 | PTGS2 (0.56) | SERPINE1PTGS2TNKSTNKS2PARP1 | |
| SCHEMBL29031838 | 0.83 | PTGS2 (0.55) | SERPINE1PTGS2TNKSTNKS2PARP2 | |
| SCHEMBL29031884 | 0.83 | SERPINE1 (0.71) | SERPINE1PTGS2TNKSTNKS2PARP2 | |
| SCHEMBL30472337 | 0.83 | PTGS2 (0.55) | SERPINE1PTGS2TNKSTNKS2PARP2 | |
| SCHEMBL29639170 | 0.83 | SERPINE1 (0.71) | SERPINE1PTGS2TNKSTNKS2PARP2 | |
| SCHEMBL29639169 | 0.83 | PTGS2 (0.56) | SERPINE1PTGS2TNKSTNKS2PARP1 | |
| SCHEMBL29031861 | 0.82 | CSF1R (0.54) | SERPINE1PTGS2PARP1ESR1ESR2 | |
| SCHEMBL31047696 | 0.81 | SERPINE1 (0.69) | SERPINE1PTGS2TNKSTNKS2PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496166-A | Preparation method of phthalazinone compound | 五邑大学 | 2024-08-16 | — | — | CN | disclosed |