SCHEMBL3212919

SCHEMBL3212919

c1ccc2c(c1)[nH]c1nccn12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
RXFP1 Q9HBX9 2/20 0.46
PARP1 P09874 1/20 0.46
PDE2A O00408 1/20 0.41
PDE6D O43924 1/20 0.41
PDE8A O60658 1/20 0.41
PDE5A O76074 1/20 0.41
PDE9A O76083 1/20 0.41
PDE8B O95263 1/20 0.41
PDE6A P16499 1/20 0.41
PDE6G P18545 1/20 0.41
PDE4A P27815 1/20 0.41
PDE6B P35913 1/20 0.41
PDE6C P51160 1/20 0.41
PDE1A P54750 1/20 0.41
PDE1B Q01064 1/20 0.41
PDE4B Q07343 1/20 0.41
PDE4C Q08493 1/20 0.41
PDE4D Q08499 1/20 0.41
PDE3B Q13370 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20893090 0.79 KDR (0.37) PDE3BPDE3ACHEK1MAP4K4CSF1R
SCHEMBL11880273 0.75 PDE7A (0.42) ALDH1A1RXFP1PARP1PDE2APDE6D
SCHEMBL20893215 0.75 PSMB8 (0.42) ALDH1A1RXFP1POLBKDM4EDAO
SCHEMBL12638629 0.75 PARP1 (0.41) PARP1PDE2APDE6DPDE8APDE5A
SCHEMBL6713740 0.75 ALDH1A1 (0.45) ALDH1A1PARP1PDE2APDE6DPDE8A
SCHEMBL2818529 0.75 PDE2A (0.69) ALDH1A1RXFP1PARP1PDE2APDE6D
SCHEMBL30273078 0.75 PDE2A (0.69) ALDH1A1RXFP1PARP1PDE2APDE6D
SCHEMBL31731798 0.73 MAPK8 (0.40) ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2
SCHEMBL31731811 0.73 MAPK8 (0.40) ALDH1A1PARP1KDM4EKMT2ASMN1; SMN2
SCHEMBL5351084 0.73 PARP1 (0.50) ALDH1A1RXFP1PARP1POLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3899034-B1 METHODS FOR RNA ANALYSIS CureVac SE (DE) 2026-03-18 EP claimed
US-20230201206-A1 METHODS FOR KILLING ANTIBIOTIC TOLERANT BACTERIA THE PENN STATE RESEARCH FOUNDATION 2023-06-29 US claimed
EP-3899034-A1 METHODS FOR RNA ANALYSIS CureVac AG (DE) 2021-10-27 EP claimed
WO-2020127959-A1 METHODS FOR RNA ANALYSIS CUREVAC AG (DE) 2020-06-25 WO claimed
EP-0607076-A1 9H-Imidazo 1,2-a benzimidazole derivatives with GABA activity SYNTHELABO (FR) 1994-07-20 EP claimed
JP-6271575-A None JP disclosed
EP-3899034-B1 METHODS FOR RNA ANALYSIS CureVac SE (DE) 2026-03-18 EP disclosed
US-12538704-B2 4H-imidazo[1,2-a]imidazoles for electronic applications UDC IRELAND LIMITED (IE) 2026-01-27 US disclosed
US-12492425-B2 Methods for RNA analysis CureVac SE (DE) 2025-12-09 US disclosed
US-20250353862-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-11-20 US disclosed
EP-4547671-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2025-05-07 EP disclosed
US-20250042902-A1 TRICYCLIC CRBN LIGANDS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2025-02-06 US disclosed
US-5639756-A ANTIDIABETIC AGENTS ADIR ET COMPAGNIE (FR) 1997-06-17 US disclosed
US-5623073-A ANTIDIABETIC AGENT ADIR ET COMPAGNIE (FR) 1997-04-22 US disclosed
WO-1996021662-A1 THE USE OF HETEROCYCLIC COMPOUNDS AS ANTIOXIDANTS, RADICAL SCAVENGERS, Fe2+ COMPLEXING AGENTS, TISSUE- AND/OR NEUROPROTECTANTS RISE FRODE (NO) 1996-07-18 WO disclosed
US-5466706-A Compounds for hypnotics, anxiety or anticonvulsants SYNTHELABO (FR) 1995-11-14 US disclosed
JP-H06271575-A 9H-IMIDAZO(1,2-A)BENZIMIDAZOLE-3-ACETOAMIDE DERIVATIVE, ITS PREPARATION AND ITS APPLICATION TO THERAPY SYNTHELABO SA 1994-09-27 JP disclosed
EP-0607076-A1 9H-Imidazo 1,2-a benzimidazole derivatives with GABA activity SYNTHELABO (FR) 1994-07-20 EP disclosed
US-5149700-A Antiarrhythmic agent AMERICAN HOME PRODUCTS CORPORATION (US) 1992-09-22 US disclosed
WO-1991018904-A1 SUBSTITUTED ARYLSULFONAMIDES AND BENZAMIDES AMERICAN HOME PRODUCTS CORPORATION (US) 1991-12-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12538704-B2 4H-imidazo[1,2-a]imidazoles for electronic applications RIF1, NR2E1, NR3C1 ALDH1A1 680/4885RXFP1 678/4885PARP1 602/4885
US-20250042902-A1 TRICYCLIC CRBN LIGANDS AND USES THEREOF CRBN, CRKL, CUL4A ALDH1A1 4128/4885RXFP1 4238/4885PARP1 2805/4885
US-20250353862-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 ALDH1A1 4445/4885RXFP1 4840/4885PARP1 1995/4885
US-20230201206-A1 METHODS FOR KILLING ANTIBIOTIC TOLERANT BACTERIA CLPP, SPOUT1, CASP3 ALDH1A1 942/4885RXFP1 4086/4885PARP1 2207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.