Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.63 |
| ▸ | HTR2C | P28335 | 3/20 | 0.63 |
| ▸ | HTR6 | P50406 | 2/20 | 0.63 |
| ▸ | ESR1 | P03372 | 4/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | MAT2A | P31153 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14448753 | 0.80 | HTR6 (0.62) | HTR2AHTR2CHTR6KDM4EALDH1A1 | |
| SCHEMBL5332251 | 0.78 | KDM4E (0.57) | HTR2AHTR2CHTR6ELANEKDM4E | |
| SCHEMBL1173877 | 0.78 | KIF11 (0.52) | HTR2AHTR2CHTR6MAT2AKDM4E | |
| SCHEMBL5441431 | 0.78 | MEN1 (0.54) | HTR2AHTR2CHTR6MAT2AKDM4E | |
| SCHEMBL7959818 | 0.78 | HTR2C (1.00) | HTR2AHTR2CHTR6ESR1ESR2 | |
| SCHEMBL28773723 | 0.77 | ESR1 (0.54) | HTR2AHTR2CHTR6ESR1ESR2 | |
| SCHEMBL18787054 | 0.76 | ESR1 (0.87) | HTR2AHTR2CHTR6ESR1ESR2 | |
| SCHEMBL3395044 | 0.75 | AHR (0.46) | HTR2AHTR2CHTR6ESR2ELANE | |
| SCHEMBL29033508 | 0.74 | HTR6 (0.58) | HTR2AHTR2CHTR6ESR1ESR2 | |
| SCHEMBL29799621 | 0.74 | ESR1 (1.00) | HTR2AHTR2CHTR6ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178243-B | Preparation method and application of (hetero) aryl fused carbazole compound | 西南医科大学 | 2024-11-22 | — | — | CN | disclosed |
| CN-116178243-A | Preparation method and application of (hetero) aryl fused carbazole compound | 西南医科大学 | 2023-05-30 | — | — | CN | disclosed |