Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.58 |
| ▸ | HTR2A | P28223 | 3/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 3/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.51 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | CCND1 | P24385 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10533610 | 0.83 | HTR6 (0.68) | HTR6HTR2AHTR2CLMNAKDM4E | |
| SCHEMBL8524450 | 0.81 | LMNA (0.56) | HTR6HTR2AHTR2CLMNAKDM4E | |
| SCHEMBL16862164 | 0.77 | QDPR (0.67) | HTR6LMNAKDM4EPOLBHTR1A | |
| SCHEMBL50923 | 0.77 | QDPR (0.67) | HTR6LMNAKDM4EPOLBHTR1A | |
| Bromide SCHEMBL11557389 | 0.76 | QDPR (0.65) | HTR6LMNAKDM4EPOLBHTR1A | |
| Ammonia Solution, Strong SCHEMBL15875021 | 0.76 | QDPR (0.65) | HTR6LMNAKDM4EPOLBHTR1A | |
| Hydrochloric Acid SCHEMBL1148906 | 0.76 | QDPR (0.65) | HTR6LMNAKDM4EPOLBHTR1A | |
| SCHEMBL29033503 | 0.74 | HTR2A (0.63) | HTR6HTR2AHTR2CKDM4EESR1 | |
| Hydrochloric Acid SCHEMBL19717522 | 0.74 | QDPR (0.62) | HTR6LMNAKDM4EPOLBHTR1A | |
| SCHEMBL13898494 | 0.74 | QDPR (0.68) | HTR6LMNAKDM4EPOLBHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178243-B | Preparation method and application of (hetero) aryl fused carbazole compound | 西南医科大学 | 2024-11-22 | — | — | CN | disclosed |
| CN-116178243-A | Preparation method and application of (hetero) aryl fused carbazole compound | 西南医科大学 | 2023-05-30 | — | — | CN | disclosed |