Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29209110 | 0.85 | OPRM1 (0.39) | BRD4OPRM1OPRK1OPRD1PGR | |
| SCHEMBL29033541 | 0.79 | ALDH1A1 (0.47) | OPRM1SRD5A1MAPTALOX15ALOX12 | |
| SCHEMBL11091178 | 0.76 | DRD1 (0.45) | OPRM1MAPTHSD17B10 | |
| SCHEMBL29516233 | 0.73 | BRD4 (0.42) | BRD4MAPTKMT2AMEN1TP53 | |
| SCHEMBL26956225 | 0.73 | BRD4 (0.42) | BRD4MAPTKMT2AMEN1TP53 | |
| SCHEMBL26956222 | 0.73 | BRD4 (0.42) | BRD4GABRA1GABRB2MAPTKMT2A | |
| SCHEMBL1655895 | 0.72 | NOTUM (0.43) | MAPTKMT2AMEN1HSD17B10SMN1; SMN2 | |
| SCHEMBL8644828 | 0.72 | TUBB4A (0.38) | BRD4OPRM1OPRK1OPRD1GABRA1 | |
| SCHEMBL27655629 | 0.70 | OPRM1 (0.39) | OPRM1OPRK1OPRD1GABRA1GABRB2 | |
| SCHEMBL8644832 | 0.70 | TUBB4A (0.37) | BRD4GABRA1GABRB2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049746-A1 | COMPOSITIONS COMPRISING WERNER SYNDROME HELICASE INHIBITORS AND METHODS OF USING THE SAME | EIKON THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |
| CN-117999259-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-110128843-B | Fluorescent dye and preparation method and application thereof | 深圳大学 | 2023-07-14 | — | — | CN | disclosed |