Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29033971 | 0.87 | HDAC1 (0.42) | MAPTKDM4EL3MBTL1TDP1MEN1 | |
| SCHEMBL29033966 | 0.85 | KDM1A (0.51) | MAPTKDM4EL3MBTL1TDP1NR1I3 | |
| SCHEMBL4449942 | 0.80 | ALDH1A1 (0.52) | MAPTKDM4ETDP1MAPK1MEN1 | |
| SCHEMBL30502863 | 0.78 | KDM4E (0.50) | MAPTKDM4EL3MBTL1TDP1NR1I3 | |
| SCHEMBL29033970 | 0.78 | KDM4E (0.50) | MAPTKDM4EL3MBTL1TDP1NR1I3 | |
| SCHEMBL27858170 | 0.75 | KDM1A (0.52) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL26192842 | 0.75 | HDAC3 (0.42) | MAPTKDM4EMAPK1MEN1KMT2A | |
| SCHEMBL25258840 | 0.74 | ALDH1A1 (0.51) | MAPTKDM4ETDP1MEN1KMT2A | |
| SCHEMBL31128113 | 0.74 | LMNA (0.57) | MAPTKDM4EL3MBTL1TDP1NR1I3 | |
| SCHEMBL7494123 | 0.73 | RAB9A (0.68) | MAPTKDM4EL3MBTL1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444436-A | Synthesis method of aminophenylpyrazole compound | 曲靖师范学院 | 2023-07-18 | — | — | CN | disclosed |