Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27858170 | 0.90 | KDM1A (0.52) | KDM1AHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL29033966 | 0.88 | KDM1A (0.51) | KDM1AHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL29033971 | 0.85 | HDAC1 (0.42) | KDM1AHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL29033973 | 0.81 | KDM1A (0.54) | KDM1AHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL30502867 | 0.81 | KDM1A (0.54) | KDM1AHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL1861673 | 0.74 | KMT2A (0.49) | MAPTSMN1; SMN2HSP90AA1HSP90AB1DCTPP1 | |
| SCHEMBL29033977 | 0.73 | KDM1A (0.53) | KDM1AHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL29033974 | 0.73 | MAPT (0.50) | HDAC1HDAC2HDAC8HDAC6HDAC5 | |
| SCHEMBL30502860 | 0.73 | KDM1A (0.53) | KDM1AHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL4307777 | 0.72 | CACNA1G (0.54) | KDM1AHDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444436-A | Synthesis method of aminophenylpyrazole compound | 曲靖师范学院 | 2023-07-18 | — | — | CN | disclosed |