Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29034603 | 0.84 | PDE4B (0.40) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL29034606 | 0.77 | TDP1 (0.44) | TDP1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL18736532 | 0.73 | TDP1 (0.45) | TDP1RAB9AALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL29034609 | 0.72 | TDP1 (0.46) | TDP1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL18736367 | 0.71 | RAB9A (0.46) | TDP1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL6168202 | 0.70 | TDP1 (0.55) | TDP1NPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL30658879 | 0.70 | RAB9A (0.46) | TDP1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL18736368 | 0.70 | RAB9A (0.46) | TDP1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL6652205 | 0.70 | TDP1 (0.47) | TDP1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9741945 | 0.70 | TDP1 (0.62) | TDP1NPC1RAB9AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108472381-B | Compounds and therapeutic uses thereof | 森陶里治疗有限公司 | 2023-06-06 | — | — | CN | disclosed |