Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10933256 | 0.85 | ATM (0.46) | PARP1HDAC8HDAC6KMT2ATDP1 | |
| SCHEMBL27582425 | 0.82 | PARP1 (0.59) | PARP1HDAC8HDAC6SMN1; SMN2MEN1 | |
| Toluene SCHEMBL28236911 | 0.82 | CES2 (0.52) | SMN1; SMN2MEN1KMT2AHPGDPOLB | |
| Toluene SCHEMBL28236913 | 0.82 | CES2 (0.52) | SMN1; SMN2MEN1KMT2AHPGDPOLB | |
| SCHEMBL14468269 | 0.80 | PARP1 (0.52) | PARP1HDAC8HDAC6SMN1; SMN2MEN1 | |
| SCHEMBL3156993 | 0.80 | PARP1 (0.57) | PARP1HDAC8HDAC6SMN1; SMN2MEN1 | |
| SCHEMBL15494373 | 0.79 | PARP1 (0.50) | PARP1HDAC8HDAC6SMN1; SMN2MEN1 | |
| SCHEMBL10923240 | 0.79 | TPMT (0.52) | PARP1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL29034613 | 0.78 | PARP1 (0.50) | PARP1HDAC8HDAC6SMN1; SMN2MEN1 | |
| Cyanate SCHEMBL27852073 | 0.78 | PARP1 (0.55) | PARP1HDAC8HDAC6SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596885-A | Process for the preparation of phenylglyoxylic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1986-06-24 | — | — | US | claimed |
| CN-112321544-B | Chiral quaternary carbon cyanide and preparation method thereof | 深圳湾实验室坪山生物医药研发转化中心 | 2023-05-26 | — | — | CN | disclosed |
| CN-113755477-A | Nitrilase mutant and application thereof in preparation of acetophenone acid compound | 上海晖胧生物医药有限公司 | 2021-12-07 | — | — | CN | disclosed |
| CN-112321544-A | Chiral quaternary carbon cyanide and preparation method thereof | 深圳湾实验室坪山生物医药研发转化中心 | 2021-02-05 | — | — | CN | disclosed |
| EP-1200393-B1 | OXIME AMIDES AND HYDRAZONE AMIDES HAVING FUNGICIDAL ACTIVITY | MONSANTO TECHNOLOGY LLC (US) | 2003-12-10 | — | — | EP | disclosed |
| EP-1200393-A1 | OXIME AMIDES AND HYDRAZONE AMIDES HAVING FUNGICIDAL ACTIVITY | Monsanto Technology LLC (US) | 2002-05-02 | — | — | EP | disclosed |
| US-20020045655-A1 | Oxime amides and hydrazone amides having fungicidal activity | MONSANTO TECHNOLOGY LLC. | 2002-04-18 | — | — | US | disclosed |
| US-6359156-B1 | CONTROLLING DISEASES IN CEREAL PLANTS | MONSANTO TECHNOLOGY LLC | 2002-03-19 | — | — | US | disclosed |
| US-6297271-B1 | CONTROLLING TAKE-ALL DISEASE IN A PLANT | MONSANTO TECHNOLOGY LLC | 2001-10-02 | — | — | US | disclosed |
| WO-2001012590-A1 | OXYME AMIDES AND HYDRAZONE AMIDES HAVING FUNGICIDAL ACTIVITY | MONSANTO TECHNOLOGY LLC (US) | 2001-02-22 | — | — | WO | disclosed |
| US-4966913-A | FOR FALL ARMYWORM AND EUROPEAN CORN BORER | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1990-10-30 | — | — | US | disclosed |
| US-4942247-A | SULFIDE DERIVATIVES OF NITRILES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1990-07-17 | — | — | US | disclosed |
| US-4596885-A | Process for the preparation of phenylglyoxylic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1986-06-24 | — | — | US | disclosed |
| US-4108875-A | REACTING ACYL HALIDE WITH AN ALKALI METAL CYANIDE AND A COPPER(I) SALT IN THE PRESENCE OF A CARBOXYLIC ACID NITRILE WITH HEATING | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1978-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020045655-A1 | Oxime amides and hydrazone amides having fungicidal activity | AADAC, HAAO, OGA | PARP1 3656/4885HDAC8 55/4885HDAC6 587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.