Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 6/20 | 0.54 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11759394 | 0.90 | BAZ2B (0.46) | BAZ2BAKR1B10AKR1B1PTGDR2LMNA | |
| SCHEMBL10773567 | 0.85 | AKR1B10 (0.52) | AKR1B10AKR1B1PTGDR2 | |
| SCHEMBL29034617 | 0.84 | AKR1B10 (0.70) | AKR1B10AKR1B1PTGDR2LMNAPABPC1 | |
| SCHEMBL5315252 | 0.81 | BAZ2B (0.48) | BAZ2BAKR1B10AKR1B1PTGDR2LMNA | |
| SCHEMBL28603644 | 0.81 | BAZ2B (0.51) | BAZ2BPTGDR2PTGER2PTGDR | |
| SCHEMBL28606447 | 0.79 | PTGDR2 (0.56) | BAZ2BPTGDR2LMNAPTGER2PTGDR | |
| SCHEMBL13242303 | 0.77 | HDAC1 (0.50) | BAZ2B | |
| SCHEMBL5319936 | 0.76 | PTGDR2 (0.53) | BAZ2BAKR1B10AKR1B1PTGDR2LMNA | |
| SCHEMBL11670078 | 0.75 | AKR1B10 (0.43) | AKR1B10AKR1B1SMN1; SMN2 | |
| SCHEMBL5316996 | 0.74 | TP53 (0.53) | BAZ2BAKR1B10AKR1B1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116425670-A | Novel heterocyclic compounds as TEAD inhibitors | 英矽智能科技(上海)有限公司 | 2023-07-14 | — | — | CN | claimed |
| CN-116425670-A | Novel heterocyclic compounds as TEAD inhibitors | 英矽智能科技(上海)有限公司 | 2023-07-14 | — | — | CN | disclosed |