Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 1/20 | 0.70 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.70 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | USP14 | P54578 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10773567 | 0.84 | AKR1B10 (0.52) | AKR1B10AKR1B1PTGDR2 | |
| SCHEMBL29034623 | 0.84 | BAZ2B (0.54) | AKR1B10AKR1B1PTGDR2MEN1KMT2A | |
| SCHEMBL600037 | 0.79 | AKR1B10 (0.70) | AKR1B10AKR1B1PTGDR2SMN1; SMN2HSD17B10 | |
| SCHEMBL29034621 | 0.75 | PTGDR2 (0.46) | PTGDR2 | |
| SCHEMBL601773 | 0.75 | AKR1B10 (0.64) | AKR1B10AKR1B1PTGDR2MAOAMAOB | |
| SCHEMBL11670078 | 0.74 | AKR1B10 (0.43) | AKR1B10AKR1B1SMN1; SMN2ALDH1A1USP14 | |
| SCHEMBL11759394 | 0.74 | BAZ2B (0.46) | AKR1B10AKR1B1PTGDR2MEN1KMT2A | |
| SCHEMBL13368698 | 0.73 | HTR6 (0.66) | MAOAMAOB | |
| SCHEMBL12868564 | 0.73 | LMNA (0.78) | AKR1B10AKR1B1SMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL13062133 | 0.73 | PTGDR2 (0.51) | AKR1B10AKR1B1PTGDR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116425670-A | Novel heterocyclic compounds as TEAD inhibitors | 英矽智能科技(上海)有限公司 | 2023-07-14 | — | — | CN | claimed |
| CN-116425670-A | Novel heterocyclic compounds as TEAD inhibitors | 英矽智能科技(上海)有限公司 | 2023-07-14 | — | — | CN | disclosed |