Sulfuric Acid

Sulfuric Acid

SCHEMBL29034778

O=S(=O)(O)O.OC1CNC1

nearest known ligand 0.44

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAN1B1 Q9UKM7 1/20 0.44
FUCA1 P04066 4/20 0.40
GBA1 P04062 2/20 0.40
GLA P06280 2/20 0.40
GAA P10253 1/20 0.40
CA5A P35218 1/20 0.40
CA5B Q9Y2D0 1/20 0.40
GLB1 P16278 1/20 0.40
LMNA P02545 1/20 0.38
CYP3A4 P08684 1/20 0.38
GABRA1 P14867 1/20 0.38
TSHR P16473 1/20 0.38
GABRG2 P18507 1/20 0.38
NFKB1 P19838 1/20 0.38
GABRB3 P28472 1/20 0.38
GABRA5 P31644 1/20 0.38
GABRA3 P34903 1/20 0.38
GABRA2 P47869 1/20 0.38
GABRA6 Q16445 1/20 0.38
CCR5 P51681 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29034779 0.88 MAN1B1 (0.40) MAN1B1FUCA1GBA1GLAGAA
SCHEMBL48555 0.82
Sulfuric Acid SCHEMBL28874981 0.81 GABRA5 (0.46) CA5ACA5BLMNACYP3A4GABRA1
Hydrochloric Acid SCHEMBL27450396 0.78
SCHEMBL3343202 0.78 MAN1B1 (0.57) MAN1B1FUCA1GBA1GLAGAA
Methane SCHEMBL28046548 0.78
Bromide SCHEMBL27700910 0.78
Ethane SCHEMBL9684365 0.74
Methane SCHEMBL28870704 0.74
Hydrochloric Acid SCHEMBL221781 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116425720-A Preparation method of delafloxacin meglumine 广东东阳光药业有限公司 2023-07-14 CN claimed
CN-116425720-A Preparation method of delafloxacin meglumine 广东东阳光药业有限公司 2023-07-14 CN disclosed