Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.57 |
| ▸ | GBA1 | P04062 | 6/20 | 0.50 |
| ▸ | FUCA1 | P04066 | 4/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | GLB1 | P16278 | 2/20 | 0.50 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48555 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL27450396 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL24204 | 0.91 | — | — | |
| Bromide SCHEMBL27700910 | 0.91 | — | — | |
| Methane SCHEMBL28046548 | 0.91 | — | — | |
| Methane SCHEMBL28870704 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL221781 | 0.87 | — | — | |
| Ethane SCHEMBL9684365 | 0.87 | — | — | |
| SCHEMBL1992553 | 0.84 | — | — | |
| SCHEMBL16906285 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160626-A1 | Process For The Preparation Of 3,7-Dihydroxy-1,5-Diazacyclooctanes | ASTRAZENECA AB (SE) | 2010-06-24 | — | — | US | disclosed |
| US-20100160626-A1 | Process For The Preparation Of 3,7-Dihydroxy-1,5-Diazacyclooctanes | ASTRAZENECA AB (SE) | 2010-06-24 | — | — | US | disclosed |
| US-20090240051-A1 | New process for the production of oxabispidines | ASTRAZENECA AB (SE) | 2009-09-24 | — | — | US | disclosed |
| US-20090036675-A1 | New process for production of oxabispidines | ASTRAZENECA AB (SE) | 2009-02-05 | — | — | US | disclosed |
| US-7439355-B2 | Process for the production of oxabispidines | ASTRAZENECA AB (SE) | 2008-10-21 | — | — | US | disclosed |
| CN-101203520-A | Process for the preparation of 3,7-dihydroxy-1,5-diazacyclooctanes | ASTRAZENECA AB (SE) | 2008-06-18 | — | — | CN | disclosed |
| EP-1900741-A1 | New process for the production of oxabispidines | AstraZeneca AB (SE) | 2008-03-19 | — | — | EP | disclosed |
| EP-1896486-A1 | PROCESS FOR THE PREPARATION OF 3,7-DIHYDROXY-1,5-DIAZACYCLOOCTANES | AstraZeneca AB (SE) | 2008-03-12 | — | — | EP | disclosed |
| US-20070197519-A1 | New Process For The Preparation Of Oxabispidines | ASTRAZENECA AB (SE) | 2007-08-23 | — | — | US | disclosed |
| US-7169921-B2 | Process for the preparation of oxabispidines | ASTRAZENECA AB (SE) | 2007-01-30 | — | — | US | disclosed |
| US-20050171100-A1 | Process for the production of oxabispidines | ASTRAZENECA AB (SE) | 2005-08-04 | — | — | US | disclosed |
| EP-1385850-B1 | NEW PROCESS FOR THE PREPARATION OF OXABISPIDINES | ASTRAZENECA AB (SE) | 2004-12-08 | — | — | EP | disclosed |
| US-20040181060-A1 | Process for the preparation of oxabispidines | ASTRAZENECA AB (SE) | 2004-09-16 | — | — | US | disclosed |
| US-20040133000-A1 | Process for the preparation of oxabispidines | ASTRAZENECA AB (SE) | 2004-07-08 | — | — | US | disclosed |
| EP-1385851-A1 | NEW PROCESS FOR THE PREPARATION OF OXABISPIDINES | AstraZeneca AB (SE) | 2004-02-04 | — | — | EP | disclosed |
| EP-1385850-A1 | NEW PROCESS FOR THE PREPARATION OF OXABISPIDINES | AstraZeneca AB (SE) | 2004-02-04 | — | — | EP | disclosed |
| EP-1330462-A1 | NEW PROCESS FOR THE PRODUCTION OF OXABISPIDINES | AstraZeneca AB (SE) | 2003-07-30 | — | — | EP | disclosed |
| WO-2002083691-A1 | NEW PROCESS FOR THE PREPARATION OF OXABISPIDINES | ASTRAZENECA AB (SE) | 2002-10-24 | — | — | WO | disclosed |
| WO-2002083690-A1 | NEW PROCESS FOR THE PREPARATION OF OXABISPIDINES | ASTRAZENECA AB (SE) | 2002-10-24 | — | — | WO | disclosed |
| WO-2002028864-A1 | NEW PROCESS FOR THE PRODUCTION OF OXABISPIDINES | ASTRAZENECA AB (SE) | 2002-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171100-A1 | Process for the production of oxabispidines | AVPR1B, CCNB3, CCNB1 | MAN1B1 252/4885GBA1 665/4885FUCA1 2813/4885 |
| US-20090240051-A1 | New process for the production of oxabispidines | AVPR1B, CCNB1, QDPR | MAN1B1 160/4885GBA1 850/4885FUCA1 2961/4885 |
| US-20090036675-A1 | New process for production of oxabispidines | AVPR1B, CCNB1, DHPS | MAN1B1 143/4885GBA1 943/4885FUCA1 3096/4885 |
| US-20040133000-A1 | Process for the preparation of oxabispidines | CYP1B1, ATP1B1, MAOB | MAN1B1 29/4885GBA1 316/4885FUCA1 1307/4885 |
| US-20070197519-A1 | New Process For The Preparation Of Oxabispidines | TST, IDH3B, INTS6 | MAN1B1 1985/4885GBA1 4123/4885FUCA1 4293/4885 |
| US-20040181060-A1 | Process for the preparation of oxabispidines | ADH1C, ADH1A, CYP2E1 | MAN1B1 398/4885GBA1 3755/4885FUCA1 3362/4885 |
| US-20100160626-A1 | Process For The Preparation Of 3,7-Dihydroxy-1,5-Diazacyclooctanes | CYP2D6, KCNH1, CYP2B6 | MAN1B1 859/4885GBA1 1934/4885FUCA1 4310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.