SCHEMBL29034876

SCHEMBL29034876

CC(C)(C)OP(=O)(O)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.48
CA4 P22748 2/20 0.48
CA5A P35218 2/20 0.48
TSHR P16473 3/20 0.46
ALDH1A1 P00352 5/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
GAA P10253 1/20 0.44
PKM P14618 1/20 0.44
CFTR P13569 1/20 0.43
DGAT1 O75907 1/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
ALOX15 P16050 1/20 0.41
ESR1 P03372 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9000844 0.86 ALDH1A1 (0.47) CA2CA4CA5ATSHRALDH1A1
SCHEMBL29115755 0.82 CA2 (0.43) CA2CA4CA5ATSHRALDH1A1
SCHEMBL27944332 0.80 CA2 (0.45) CA2CA4CA5ATSHRALDH1A1
SCHEMBL11333601 0.79 CA2 (0.48) CA2CA4CA5ATSHRALDH1A1
SCHEMBL11470057 0.79 CA2 (0.48) CA2CA4CA5ATSHRALDH1A1
SCHEMBL27333189 0.78 L3MBTL1 (0.50) CA2CA4CA5ATSHRALDH1A1
SCHEMBL28519671 0.78 ALDH1A1 (0.52) CA2CA4CA5ATSHRALDH1A1
SCHEMBL17488912 0.76 TSHR (0.47) CA2CA4CA5ATSHRALDH1A1
SCHEMBL344018 0.76 CA2 (0.54) CA2CA4CA5ATSHRALDH1A1
SCHEMBL27603983 0.75 TSHR (0.46) CA2CA4CA5ATSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116425794-A Aryl phosphonate compound and preparation method thereof 烟台大学 2023-07-14 CN claimed
CN-116425794-A Aryl phosphonate compound and preparation method thereof 烟台大学 2023-07-14 CN disclosed