Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28388309 | 0.96 | PKM (0.59) | PKMHTTHPGDCA4L3MBTL1 | |
| SCHEMBL331195 | 0.86 | L3MBTL1 (0.67) | PKMHTTCA4L3MBTL1TDP1 | |
| SCHEMBL35394 | 0.86 | L3MBTL1 (0.60) | PKMHTTHPGDCA4L3MBTL1 | |
| SCHEMBL31472733 | 0.85 | PKM (0.54) | PKMHTTHPGDCA4L3MBTL1 | |
| SCHEMBL29023907 | 0.85 | L3MBTL1 (0.55) | PKMHTTHPGDCA4L3MBTL1 | |
| SCHEMBL29207963 | 0.84 | L3MBTL1 (0.64) | PKMHTTCA4L3MBTL1TDP1 | |
| Phosphine SCHEMBL28875449 | 0.84 | L3MBTL1 (0.64) | PKMHTTCA4L3MBTL1TDP1 | |
| SCHEMBL28388783 | 0.84 | HCRTR1 (0.59) | PKMHTTCA4L3MBTL1TDP1 | |
| SCHEMBL28685381 | 0.83 | PKM (0.53) | PKMHTTHPGDCA4L3MBTL1 | |
| SCHEMBL29107147 | 0.83 | L3MBTL1 (0.53) | PKMHTTHPGDCA4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117586304-A | Aryl phosphonate and aryl thiophosphonate compound and preparation method thereof | 烟台大学 | 2024-02-23 | — | — | CN | disclosed |
| CN-116425794-A | Aryl phosphonate compound and preparation method thereof | 烟台大学 | 2023-07-14 | — | — | CN | disclosed |