Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | AOC2 | O75106 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29035288 | 0.81 | POLB (0.51) | MAOBKDM4ESMN1; SMN2POLBMAPT | |
| SCHEMBL30530685 | 0.80 | KDM4E (0.53) | MAOBKDM4ESMN1; SMN2LTA4HFAAH | |
| SCHEMBL6329715 | 0.79 | LTA4H (0.54) | KDM4ESMN1; SMN2LTA4HFAAHMAPT | |
| SCHEMBL3256041 | 0.76 | LTA4H (0.61) | KDM4ESMN1; SMN2LTA4HL3MBTL1 | |
| SCHEMBL3257350 | 0.76 | BRD4 (0.54) | KDM4ESMN1; SMN2LTA4HFAAHMAPT | |
| SCHEMBL25362868 | 0.75 | SMN1; SMN2 (0.49) | KDM4ESMN1; SMN2LTA4HFAAH | |
| SCHEMBL13692338 | 0.75 | KDM4E (0.55) | MAOBKDM4ESMN1; SMN2LTA4HFAAH | |
| SCHEMBL8806419 | 0.75 | KDM4E (0.51) | KDM4ESMN1; SMN2LTA4HFAAHPOLB | |
| SCHEMBL10552333 | 0.74 | L3MBTL1 (0.59) | SMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL6330955 | 0.74 | KDM4E (0.55) | KDM4ESMN1; SMN2LTA4HFAAHMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116437913-A | Pharmaceutical compounds for treating complement-mediated disorders | 艾其林医药公司 | 2023-07-14 | — | — | CN | disclosed |