Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ADH4 | P08319 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8117589 | 0.91 | CA2 (0.37) | OPRM1DNM1CA2TSHR | |
| SCHEMBL9206614 | 0.81 | OPRM1 (0.46) | OPRM1SPHK1LMNADNM1ADH1B | |
| SCHEMBL7090425 | 0.81 | OPRM1 (0.46) | OPRM1SPHK1LMNADNM1ADH1B | |
| SCHEMBL2289710 | 0.81 | LMNA (0.36) | LMNATSHR | |
| SCHEMBL11491167 | 0.81 | OPRM1 (0.46) | OPRM1SPHK1LMNADNM1ADH1B | |
| SCHEMBL9211114 | 0.79 | OPRM1 (0.48) | OPRM1SPHK1LMNADNM1ADH1B | |
| SCHEMBL28846487 | 0.78 | TSHR (0.50) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL28264637 | 0.78 | TSHR (0.50) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL28399942 | 0.78 | TSHR (0.50) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL23040337 | 0.76 | TSHR (0.47) | OPRM1SPHK1LMNADNM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116437913-A | Pharmaceutical compounds for treating complement-mediated disorders | 艾其林医药公司 | 2023-07-14 | — | — | CN | disclosed |