Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK14 | O94921 | 11/20 | 0.51 |
| ▸ | CCNY | Q8ND76 | 11/20 | 0.51 |
| ▸ | CDK2 | P24941 | 6/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.51 |
| ▸ | CDK9 | P50750 | 3/20 | 0.51 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.51 |
| ▸ | CDK1 | P06493 | 3/20 | 0.51 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.51 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.51 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.51 |
| ▸ | CDK4 | P11802 | 2/20 | 0.51 |
| ▸ | CASK | O14936 | 1/20 | 0.51 |
| ▸ | CDKL5 | O76039 | 1/20 | 0.51 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.51 |
| ▸ | MAK | P20794 | 1/20 | 0.51 |
| ▸ | CDK11B | P21127 | 1/20 | 0.51 |
| ▸ | CCND1 | P24385 | 1/20 | 0.51 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.51 |
| ▸ | CCND3 | P30281 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL954955 | 0.86 | KMT2A (0.51) | CDK14CCNYCDK2CCNA2CDK5 | |
| At-7519 SCHEMBL955568 | 0.83 | CDK5 (0.67) | CDK14CCNYCDK2CCNA2CDK5 | |
| SCHEMBL4488401 | 0.82 | CDK14 (0.48) | CDK14CCNYCDK2CCNA2CDK5 | |
| At-7519 SCHEMBL953647 | 0.82 | CDK5 (0.66) | CDK14CCNYCDK2CCNA2CDK5 | |
| At-7519 SCHEMBL31046986 | 0.82 | CDK5 (0.66) | CDK14CCNYCDK2CCNA2CDK5 | |
| At-7519 SCHEMBL1069453 | 0.81 | CDK5 (0.62) | CDK14CCNYCDK2CCNA2CDK5 | |
| SCHEMBL29035532 | 0.81 | CDK2 (0.47) | CDK14CCNYCDK2CCNA2CDK5 | |
| SCHEMBL8219606 | 0.81 | TYK2 (0.52) | CDK14CCNYMEN1KMT2ATYK2 | |
| SCHEMBL8261519 | 0.79 | CDK5 (0.49) | CDK14CCNYCDK2CCNA2CDK5 | |
| SCHEMBL1645592 | 0.78 | JAK2 (0.52) | CDK14CCNYCDK2CCNA2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109705090-B | Tartaric acid addition salts of 3, 4-disubstituted 1H-pyrazole compounds and crystalline forms thereof | 上海君实生物医药科技股份有限公司 | 2023-06-20 | — | — | CN | claimed |