SCHEMBL658053

SCHEMBL658053

COC(=O)CNc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.54
ALDH1A1 P00352 3/20 0.54
RAB9A P51151 2/20 0.54
MAPT P10636 2/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.53
NPC1 O15118 1/20 0.53
HPGD P15428 1/20 0.53
AGTR1 P30556 1/20 0.53
PKM P14618 1/20 0.47
POLB P06746 1/20 0.47
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
ERCC1 P07992 1/20 0.45
ERCC4 Q92889 1/20 0.45
TSHR P16473 2/20 0.44
HIF1A Q16665 3/20 0.44
KDM4E B2RXH2 1/20 0.44
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28330086 0.98 LMNA (0.53) LMNAALDH1A1RAB9AMAPTMEN1
Hydrochloric Acid SCHEMBL76327 0.98 LMNA (0.53) LMNAALDH1A1RAB9AMAPTMEN1
Sulfur Dioxide SCHEMBL28176580 0.94 LMNA (0.50) LMNAALDH1A1RAB9AMAPTMEN1
SCHEMBL460030 0.93 ALDH1A1 (0.49) LMNAALDH1A1RAB9AMAPTMEN1
Sulfuric Acid SCHEMBL5004844 0.93 ALDH1A1 (0.49) LMNAALDH1A1RAB9AMAPTMEN1
Hydrochloric Acid SCHEMBL8015558 0.91 MEN1 (0.48) LMNAALDH1A1RAB9AMAPTMEN1
Nitric Acid SCHEMBL27965091 0.89 ALDH1A1 (0.47) LMNAALDH1A1RAB9AMAPTMEN1
SCHEMBL28161510 0.89 ALDH1A1 (0.47) LMNAALDH1A1RAB9AMAPTMEN1
Cadaverine Tartrate SCHEMBL28296884 0.89 MAPT (0.47) LMNAALDH1A1RAB9AMAPTMEN1
SCHEMBL11743349 0.89 POLB (0.47) LMNAALDH1A1RAB9AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 915 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120699943-B Penicillin acylase for synthesizing beta-lactam antibiotics 浙江师范大学行知学院 2026-05-15 CN claimed
CN-119932000-A Penicillin G acylase AxPGA mutant, expression plasmid, genetically engineered bacterium and application 浙江昂利康制药股份有限公司 2025-05-06 CN claimed
CN-119409631-A 2,2 '-Biquinoline-4, 4' -dicarboxylic acid amino acid derivative, and preparation method and application thereof 武汉大学人民医院(湖北省人民医院) 2025-02-11 CN claimed
CN-119020335-A Penicillin acylase mutant and application thereof 浙江师范大学行知学院 2024-11-26 CN claimed
CN-118151490-B Photosensitive resin composition, photosensitive dry film and application thereof 湖南初源新材料股份有限公司 2024-08-13 CN claimed
CN-118239879-A Method for preparing 3-substituted oxindole, dihydroisoindigo and tetra-substituted ethane based on primary amine and application of primary amine 泰山学院 2024-06-25 CN claimed
CN-118185913-A Paracoccus-derived amidase and application of mutant thereof 河北科技大学 2024-06-14 CN claimed
CN-118151490-A Photosensitive resin composition, photosensitive dry film and application thereof 湖南初源新材料股份有限公司 2024-06-07 CN claimed
US-20240027442-A1 TEST REAGENT WITH IMPROVED SPECIFICITY BY SUPPRESSING FALSE NEGATIVES DENKA COMPANY LIMITED (JP) 2024-01-25 US claimed
US-20240011978-A1 TEST KIT WITH IMPROVED SPECIFICITY BY SUPPRESSING FALSE POSITIVES DENKA COMPANY LIMITED (JP) 2024-01-11 US claimed
WO-2000004024-A1 ANTIPARASITIC ARTEMISININ DERIVATIVES (ENDOPEROXIDES) BAYER AKTIENGESELLSCHAFT (DE) 2000-01-27 WO claimed
EP-0960945-A2 Enzymatic process for producing beta-lactam antibiotics involving product recovery at pH 1 in the presence of immobilized penicillin amidase Unifar Kimya Sanayii ve Ticaret A.S (TR) 1999-12-01 EP claimed
US-5801011-A Process for preparing cephalosporins with penicillin acylase without pH control ELI LILLY AND COMPANY (US) 1998-09-01 US claimed
US-5736518-A Peptide compounds of (L) amino acids and ring molecules, and therapeutical applications thereof POLIFARMA S.P.A. (IT) 1998-04-07 US claimed
EP-0567323-A2 Improved process for preparing cephalosporins ELI LILLY AND COMPANY (US) 1993-10-27 EP claimed
EP-0085023-A1 Process for the separation of enantiomers by partition between liquid phases CIBA-GEIGY AG (CH) 1983-08-03 EP claimed
US-4322548-A COMPRISING CONTACTING WITH A PHENYLGLYCINE ESTER KAY FRIES, INC. (US) 1982-03-30 US claimed
EP-0000932-B1 PRODUCTION OF N-ACYL-THIENAMYCINS MERCK & CO. INC. (US) 1981-10-21 EP claimed
EP-0000932-A1 Production of N-acyl-thienamycins MERCK & CO. INC. (US) 1979-03-07 EP claimed
US-4135978-A PRODUCTION OF N-ACYL-THIENAMYCINS MERCK & CO., INC. (US) 1979-01-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240027442-A1 TEST REAGENT WITH IMPROVED SPECIFICITY BY SUPPRESSING FALSE NEGATIVES SHBG, CD14, SARS1 LMNA 3181/4885ALDH1A1 4733/4885RAB9A 4095/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.