Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2312703 | 0.82 | L3MBTL1 (0.68) | MEN1KMT2AALDH1A1GAANPC1 | |
| SCHEMBL700769 | 0.81 | CA12 (0.60) | CA12MEN1KMT2AALDH1A1GAA | |
| SCHEMBL9388114 | 0.81 | CA12 (0.60) | CA12MEN1KMT2AALDH1A1GAA | |
| SCHEMBL700770 | 0.81 | CA12 (0.60) | CA12MEN1KMT2AALDH1A1GAA | |
| SCHEMBL413681 | 0.81 | CA12 (0.60) | CA12MEN1KMT2AALDH1A1GAA | |
| SCHEMBL4896487 | 0.79 | CA12 (0.84) | CA12MEN1KMT2AALDH1A1GAA | |
| SCHEMBL4896484 | 0.79 | CA12 (0.84) | CA12MEN1KMT2AALDH1A1GAA | |
| SCHEMBL14163515 | 0.79 | CA12 (0.84) | CA12MEN1KMT2AALDH1A1GAA | |
| SCHEMBL4726328 | 0.79 | RAB9A (0.60) | MEN1KMT2AALDH1A1GAARAB9A | |
| SCHEMBL10478287 | 0.78 | MAPT (0.65) | CA12MEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232070-A | Quinolinone alkaloid derivative containing acylhydrazone group on 1-site nitrogen atom and preparation method and application thereof | 太原理工大学 | 2022-10-25 | — | — | CN | claimed |
| CN-115232070-B | Quinolinone alkaloid derivative containing acylhydrazone group on 1-position nitrogen atom, and preparation method and application thereof | 太原理工大学 | 2023-06-30 | — | — | CN | disclosed |
| CN-115232070-A | Quinolinone alkaloid derivative containing acylhydrazone group on 1-site nitrogen atom and preparation method and application thereof | 太原理工大学 | 2022-10-25 | — | — | CN | disclosed |