Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30534501 | 1.00 | MAPT (0.42) | MAPTBCHECES1HTTRPS6KA2 | |
| SCHEMBL30534482 | 0.89 | ALDH1A1 (0.39) | MAPTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL29036162 | 0.89 | ALDH1A1 (0.39) | MAPTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL29036159 | 0.86 | MAPT (0.40) | MAPTHTTLMNATDP1ICMT | |
| SCHEMBL30534518 | 0.86 | MAPT (0.40) | MAPTHTTLMNATDP1ICMT | |
| SCHEMBL30534493 | 0.81 | HTT (0.47) | MAPTHTTLMNAICMTL3MBTL1 | |
| SCHEMBL29036156 | 0.81 | HTT (0.47) | MAPTHTTLMNAICMTL3MBTL1 | |
| SCHEMBL30534545 | 0.78 | ICMT (0.41) | LMNAICMTL3MBTL1ALDH1A1MAOB | |
| SCHEMBL29036155 | 0.77 | PRMT6 (0.34) | P2RX4 | |
| SCHEMBL29036163 | 0.77 | SLC6A2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116462686-A | 4-aryl (methyl) group-1, 4-benzoxazine imidazoline compound and preparation method and application thereof | 湖南科技大学 | 2023-07-21 | — | — | CN | disclosed |