Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30534506 | 1.00 | ICMT (0.40) | ICMTMAPTHTR7RAB9AMEN1 | |
| SCHEMBL30534482 | 0.83 | ALDH1A1 (0.39) | MAPTHTR7MEN1KMT2AALDH1A1 | |
| SCHEMBL29036162 | 0.83 | ALDH1A1 (0.39) | MAPTHTR7MEN1KMT2AALDH1A1 | |
| SCHEMBL30534545 | 0.83 | ICMT (0.41) | ICMTHTR7MEN1KMT2AALDH1A1 | |
| SCHEMBL29036176 | 0.83 | ICMT (0.41) | ICMTHTR7MEN1KMT2AALDH1A1 | |
| SCHEMBL30534536 | 0.82 | ICMT (0.44) | ICMTMAPTALDH1A1TP53NPC1 | |
| SCHEMBL29036164 | 0.82 | ICMT (0.44) | ICMTMAPTALDH1A1TP53NPC1 | |
| SCHEMBL30534518 | 0.81 | MAPT (0.40) | ICMTMAPTRAB9AALDH1A1MAPK1 | |
| SCHEMBL29036159 | 0.81 | MAPT (0.40) | ICMTMAPTRAB9AALDH1A1MAPK1 | |
| SCHEMBL30534501 | 0.79 | MAPT (0.42) | ICMTMAPTRAB9AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116462686-A | 4-aryl (methyl) group-1, 4-benzoxazine imidazoline compound and preparation method and application thereof | 湖南科技大学 | 2023-07-21 | — | — | CN | disclosed |