Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30534545 | 1.00 | ICMT (0.41) | ICMTMAOBLMNAALDH1A1PKM | |
| SCHEMBL29036162 | 0.85 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1MEN1KMT2AHTR7 | |
| SCHEMBL30534482 | 0.85 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1MEN1KMT2AHTR7 | |
| SCHEMBL29036167 | 0.83 | ICMT (0.40) | ICMTLMNAALDH1A1PKMHPGD | |
| SCHEMBL30534506 | 0.83 | ICMT (0.40) | ICMTLMNAALDH1A1PKMHPGD | |
| SCHEMBL29036164 | 0.82 | ICMT (0.44) | ICMTALDH1A1 | |
| SCHEMBL30534536 | 0.82 | ICMT (0.44) | ICMTALDH1A1 | |
| SCHEMBL30534535 | 0.81 | CHRM2 (0.48) | LMNACYP1A2CYP2C19 | |
| SCHEMBL29036154 | 0.81 | CHRM2 (0.48) | LMNACYP1A2CYP2C19 | |
| SCHEMBL29036159 | 0.80 | MAPT (0.40) | ICMTLMNAALDH1A1PKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116462686-A | 4-aryl (methyl) group-1, 4-benzoxazine imidazoline compound and preparation method and application thereof | 湖南科技大学 | 2023-07-21 | — | — | CN | disclosed |