Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.79 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.79 |
| ▸ | MAPT | P10636 | 1/20 | 0.79 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.79 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | TERT | O14746 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | DRD1 | P21728 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL343596 | 0.98 | SMN1; SMN2 (0.81) | SMN1; SMN2TDP1MAPTLIN28ACYP2C19 | |
| SCHEMBL10027665 | 0.95 | SMN1; SMN2 (0.75) | SMN1; SMN2TDP1MAPTLIN28ACYP2C19 | |
| SCHEMBL231092 | 0.89 | TDP1 (1.00) | SMN1; SMN2TDP1MAPTLIN28ATERT | |
| SCHEMBL29427509 | 0.89 | TDP1 (1.00) | SMN1; SMN2TDP1MAPTLIN28ATERT | |
| SCHEMBL10609540 | 0.87 | TDP1 (0.96) | SMN1; SMN2TDP1MAPTLIN28ATERT | |
| SCHEMBL15483843 | 0.86 | TDP1 (0.63) | SMN1; SMN2TDP1MAPTLIN28ACYP2C19 | |
| SCHEMBL3626637 | 0.86 | TDP1 (0.79) | SMN1; SMN2TDP1MAPTLIN28ACYP2C19 | |
| SCHEMBL138261 | 0.84 | SMN1; SMN2 (0.83) | SMN1; SMN2TDP1MAPTLIN28ATERT | |
| SCHEMBL6864949 | 0.84 | TDP1 (0.81) | SMN1; SMN2TDP1MAPTLIN28ACYP2D6 | |
| SCHEMBL15483623 | 0.83 | SMN1; SMN2 (0.58) | SMN1; SMN2TDP1MAPTLIN28ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2215096-A1 | COPPER-OXYGEN ADDUCT COMPLEXES | Justus-Liebig-Universität Gießen (DE) | 2010-08-11 | — | — | EP | disclosed |
| WO-2009052809-A1 | COPPER-OXYGEN ADDUCT COMPLEXES | JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) | 2009-04-30 | — | — | WO | disclosed |