Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.81 |
| ▸ | MAPT | P10636 | 1/20 | 0.81 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.81 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.49 |
| ▸ | DRD1 | P21728 | 3/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HRH1 | P35367 | 2/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | TERT | O14746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2903674 | 0.98 | SMN1; SMN2 (0.79) | SMN1; SMN2TDP1MAPTLIN28ACYP2C19 | |
| SCHEMBL10027665 | 0.96 | SMN1; SMN2 (0.75) | SMN1; SMN2TDP1MAPTLIN28ACYP2C19 | |
| SCHEMBL29427509 | 0.90 | TDP1 (1.00) | SMN1; SMN2TDP1MAPTLIN28AHRH1 | |
| SCHEMBL231092 | 0.90 | TDP1 (1.00) | SMN1; SMN2TDP1MAPTLIN28AHRH1 | |
| SCHEMBL10609540 | 0.88 | TDP1 (0.96) | SMN1; SMN2TDP1MAPTLIN28AHRH1 | |
| SCHEMBL15483843 | 0.88 | TDP1 (0.63) | SMN1; SMN2TDP1MAPTLIN28ACYP2C19 | |
| SCHEMBL3626637 | 0.87 | TDP1 (0.79) | SMN1; SMN2TDP1MAPTLIN28ACYP2C19 | |
| SCHEMBL6864949 | 0.85 | TDP1 (0.81) | SMN1; SMN2TDP1MAPTLIN28ACYP2D6 | |
| SCHEMBL15483623 | 0.84 | SMN1; SMN2 (0.58) | SMN1; SMN2TDP1MAPTLIN28ACYP2C19 | |
| SCHEMBL15483564 | 0.84 | SMN1; SMN2 (0.58) | SMN1; SMN2TDP1MAPTLIN28ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338600-B2 | Copper-oxygen adduct complexes, and methods of making and use | JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) | 2012-12-25 | — | — | US | claimed |
| EP-2215096-B1 | COPPER-OXYGEN ADDUCT COMPLEXES | UNIV GIESSEN JUSTUS LIEBIG (DE) | 2012-09-19 | — | — | EP | claimed |
| US-20120016127-A1 | COPPER-OXYGEN ADDUCT COMPLEXES | JUSTUS-LIEBIG-UNIVERSITAET GIESSEN (DE) | 2012-01-19 | — | — | US | claimed |
| EP-2215096-A1 | COPPER-OXYGEN ADDUCT COMPLEXES | Justus-Liebig-Universität Gießen (DE) | 2010-08-11 | — | — | EP | claimed |
| WO-2009052809-A1 | COPPER-OXYGEN ADDUCT COMPLEXES | JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) | 2009-04-30 | — | — | WO | claimed |
| US-8338600-B2 | Copper-oxygen adduct complexes, and methods of making and use | JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) | 2012-12-25 | — | — | US | disclosed |
| US-8338600-B2 | Copper-oxygen adduct complexes, and methods of making and use | JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) | 2012-12-25 | — | — | US | disclosed |
| US-8338600-B2 | Copper-oxygen adduct complexes, and methods of making and use | JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) | 2012-12-25 | — | — | US | disclosed |
| EP-2215096-B1 | COPPER-OXYGEN ADDUCT COMPLEXES | UNIV GIESSEN JUSTUS LIEBIG (DE) | 2012-09-19 | — | — | EP | disclosed |
| EP-2215096-B1 | COPPER-OXYGEN ADDUCT COMPLEXES | UNIV GIESSEN JUSTUS LIEBIG (DE) | 2012-09-19 | — | — | EP | disclosed |
| US-20120016127-A1 | COPPER-OXYGEN ADDUCT COMPLEXES | JUSTUS-LIEBIG-UNIVERSITAET GIESSEN (DE) | 2012-01-19 | — | — | US | disclosed |
| US-20120016127-A1 | COPPER-OXYGEN ADDUCT COMPLEXES | JUSTUS-LIEBIG-UNIVERSITAET GIESSEN (DE) | 2012-01-19 | — | — | US | disclosed |
| US-20120016127-A1 | COPPER-OXYGEN ADDUCT COMPLEXES | JUSTUS-LIEBIG-UNIVERSITAET GIESSEN (DE) | 2012-01-19 | — | — | US | disclosed |
| EP-2215096-A1 | COPPER-OXYGEN ADDUCT COMPLEXES | Justus-Liebig-Universität Gießen (DE) | 2010-08-11 | — | — | EP | disclosed |
| WO-2009052809-A1 | COPPER-OXYGEN ADDUCT COMPLEXES | JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) | 2009-04-30 | — | — | WO | disclosed |
| WO-2009052809-A1 | COPPER-OXYGEN ADDUCT COMPLEXES | JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) | 2009-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016127-A1 | COPPER-OXYGEN ADDUCT COMPLEXES | AOC2, AOC3, AOC1 | SMN1; SMN2 3131/4885TDP1 3504/4885MAPT 2441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.