Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TKT | P29401 | 5/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9791488 | 0.89 | KDM4E (0.42) | ALDH1A1TSHRKDM4EMEN1KMT2A | |
| SCHEMBL11203674 | 0.87 | TSHR (0.38) | ALDH1A1TSHRKDM4ETKTPRKCI | |
| SCHEMBL5160277 | 0.80 | ALDH1A1 (0.36) | ALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL62547 | 0.78 | TDP1 (0.39) | ALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL31265082 | 0.77 | HTT (0.44) | ALDH1A1KDM4EPRKCIACHE | |
| SCHEMBL3650407 | 0.76 | TAAR1 (0.48) | ALDH1A1TSHRKDM4EMEN1KMT2A | |
| SCHEMBL31265116 | 0.76 | POLB (0.34) | PRKCIACHE | |
| SCHEMBL31265115 | 0.73 | TYR (0.39) | ALDH1A1TSHRKDM4EMEN1KMT2A | |
| SCHEMBL13275538 | 0.73 | — | — | |
| SCHEMBL11436471 | 0.72 | ALDH1A1 (0.43) | ALDH1A1TSHRKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2211657-A2 | AIR OXIDATION HAIR DYE APPLICATION SYSTEM AND METHOD FOR COLORING HAIR USING THE SAME | Combe International Ltd. (US) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009058700-A2 | AIR OXIDATION HAIR DYE APPLICATION SYSTEM AND METHOD FOR COLORING HAIR USING THE SAME | COMBE INTERNATIONAL LTD. (US) | 2009-05-07 | — | — | WO | disclosed |
| US-6887281-B2 | N-heteroarylmethyl-p-phenylenediamine derivatives as well as oxidation dyeing agents containing these compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2005-05-03 | — | — | US | disclosed |
| US-20050015898-A1 | N-heteroarylmethyl-p-phenylenediamine derivatives as well as oxidation dyeing agents containing these compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050015898-A1 | N-heteroarylmethyl-p-phenylenediamine derivatives as well as oxidation dyeing agents containing these compounds | TYR, PNMT, DDT | ALDH1A1 66/4885TSHR 3830/4885KDM4E 4092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.