Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29037102 | 0.85 | ABCG2 (0.34) | KDM4ELMNAMAPTMEN1KMT2A | |
| SCHEMBL28447012 | 0.73 | DYRK1A (0.43) | KDM4ELMNAMAPTMEN1KMT2A | |
| SCHEMBL17339091 | 0.72 | CDK2 (0.46) | KDM4EALDH1A1CDC7CDK2HSP90AA1 | |
| SCHEMBL23676516 | 0.64 | PRMT5 (0.68) | PRMT5TOP1KDM4ELMNAMAPT | |
| SCHEMBL15158136 | 0.62 | KDM4E (0.41) | KDM4ELMNAMAPTMEN1KMT2A | |
| SCHEMBL15196988 | 0.62 | ALDH1A1 (0.53) | KDM4ELMNAMAPTMEN1KMT2A | |
| SCHEMBL15158090 | 0.61 | FNTA (0.56) | KDM4ELMNAMAPTMEN1KMT2A | |
| SCHEMBL20035184 | 0.59 | HRH4 (0.46) | PRMT5KDM4ELMNAMAPTHIF1A | |
| SCHEMBL17339164 | 0.57 | MAPT (0.46) | KDM4ELMNAMAPTMEN1KMT2A | |
| SCHEMBL21917612 | 0.57 | KDM4E (0.46) | KDM4ELMNAMAPTHIF1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111892579-B | Kinase inhibitors | 上海艾力斯医药科技股份有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-111875585-B | Kinase inhibitors | 上海艾力斯医药科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |