Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | GAA | P10253 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | GLA | P06280 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | BRD2 | P25440 | 1/20 | 0.31 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29037101 | 0.85 | PRMT5 (0.43) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL28447012 | 0.74 | DYRK1A (0.43) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL17339091 | 0.73 | CDK2 (0.46) | KDM4EALDH1A1HTTCDC7CDK2 | |
| SCHEMBL14629309 | 0.66 | CHEK1 (0.39) | ABCG2KMT2AGLALMNAIDO1 | |
| SCHEMBL8626651 | 0.65 | HSP90AA1 (0.46) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL15196988 | 0.62 | ALDH1A1 (0.53) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL15158136 | 0.62 | KDM4E (0.41) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL248261 | 0.60 | ALOX5AP (0.42) | ABCG2KDM4EALDH1A1GAAGLA | |
| SCHEMBL14629305 | 0.59 | KDM4E (0.44) | ABCG2KDM4EALDH1A1GAAMEN1 | |
| SCHEMBL15158090 | 0.59 | FNTA (0.56) | KDM4EALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111892579-B | Kinase inhibitors | 上海艾力斯医药科技股份有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-111875585-B | Kinase inhibitors | 上海艾力斯医药科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |