Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 19/20 | 0.46 |
| ▸ | TGFBR2 | P37173 | 5/20 | 0.46 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29037180 | 0.84 | TGFBR1 (0.59) | TGFBR1TGFBR2MAPK14 | |
| SCHEMBL18554284 | 0.78 | TGFBR1 (0.73) | TGFBR1TGFBR2 | |
| SCHEMBL29037183 | 0.74 | TGFBR1 (0.44) | TGFBR1TGFBR2 | |
| SCHEMBL18554301 | 0.71 | TGFBR1 (0.73) | TGFBR1TGFBR2 | |
| SCHEMBL29366034 | 0.69 | CCR1 (0.42) | TGFBR1TGFBR2MAPK14 | |
| SCHEMBL29366038 | 0.69 | CCR1 (0.42) | TGFBR1TGFBR2MAPK14 | |
| SCHEMBL22978898 | 0.69 | CCR1 (0.42) | TGFBR1TGFBR2MAPK14 | |
| SCHEMBL23007699 | 0.66 | TGFBR1 (0.43) | TGFBR1TGFBR2MAPK14 | |
| SCHEMBL23007684 | 0.65 | TGFBR1 (0.38) | TGFBR1TGFBR2MAPK14 | |
| SCHEMBL23007882 | 0.65 | TGFBR1 (0.39) | TGFBR1TGFBR2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116789681-A | Imidazo pyrimidine compound containing fused ring group, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-112341477-B | Imidazo pyrimidine compound containing fused ring group, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-112341477-A | Imidazo pyrimidine compound containing polycyclic group, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2021-02-09 | — | — | CN | disclosed |