SCHEMBL2903748

SCHEMBL2903748

CNCCc1cccc(OC(C)C)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.68
CHRM1 P11229 1/20 0.68
CHRM3 P20309 1/20 0.68
ACHE P22303 3/20 0.62
KDM4E B2RXH2 1/20 0.54
NSD2 O96028 1/20 0.54
ALDH1A1 P00352 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
TAAR1 Q96RJ0 4/20 0.53
NOS1 P29475 1/20 0.49
NOS2 P35228 1/20 0.49
ATM Q13315 2/20 0.48
DHFR P00374 1/20 0.47
ADRB2 P07550 1/20 0.46
ADRA2A P08913 1/20 0.46
DRD2 P14416 1/20 0.46
ADRA2C P18825 1/20 0.46
DRD1 P21728 1/20 0.46
ADRA1A P35348 1/20 0.46
DRD3 P35462 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15789848 0.83 ACHE (0.59) CHRM2CHRM1CHRM3ACHEKDM4E
SCHEMBL255100 0.83 DHFR (0.49) CHRM2CHRM1CHRM3ACHEKDM4E
SCHEMBL680560 0.81 CHRM2 (1.00) CHRM2CHRM1CHRM3ACHETAAR1
SCHEMBL30771638 0.81 CHRM2 (1.00) CHRM2CHRM1CHRM3ACHETAAR1
SCHEMBL12881236 0.81 ALOX5 (0.49) CHRM2CHRM1CHRM3ACHETAAR1
SCHEMBL11564729 0.81 ACHE (0.72) CHRM2CHRM1CHRM3ACHESMN1; SMN2
SCHEMBL8053575 0.79 FFAR4 (0.49) ACHEKDM4ENSD2ALDH1A1SMN1; SMN2
SCHEMBL14486728 0.79 DHFR (0.46) CHRM2CHRM1CHRM3ACHEKDM4E
SCHEMBL6963018 0.79 TAAR1 (0.66) ACHETAAR1DHFRDRD2DRD1
SCHEMBL1416835 0.79 CYP4F2 (0.56) ACHEKDM4ENSD2ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2220100-A2 CHIRAL CYCLOPLATINIZED COMPLEXES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN MEDICINE AND CATALYSTS Rheinisch-Westfälisch-Technische Hochschule Aachen (DE) 2010-08-25 EP disclosed
WO-2009077462-A2 CHIRAL CYCLOPLATINIZED COMPLEXES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN MEDICINE AND CATALYSTS Rheinisch-Westfälische Technische Hochschule Aachen (DE) 2009-06-25 WO disclosed