SCHEMBL29038541

SCHEMBL29038541

CCCCc1cc(Br)cc(Br)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GFER P55789 1/20 0.50
CYP3A4 P08684 1/20 0.48
TSHR P16473 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
EGFR P00533 1/20 0.46
ALOX5 P09917 4/20 0.45
PTGS2 P35354 3/20 0.44
GABRA1 P14867 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRA2 P47869 1/20 0.43
GABRB2 P47870 1/20 0.43
TYR P14679 1/20 0.43
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
MAPT P10636 3/20 0.41
ALDH1A1 P00352 1/20 0.41
POLB P06746 1/20 0.41
PLEC Q15149 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8400495 0.93 ALOX5 (0.53) GFERCYP3A4TSHRTDP1EGFR
SCHEMBL7614059 0.93 ALOX5 (0.53) GFERCYP3A4TSHRTDP1EGFR
SCHEMBL18896367 0.83 ALOX5 (0.44) CYP3A4TSHRTDP1EGFRALOX5
SCHEMBL26245557 0.83 TYR (0.42) GFERCYP3A4TSHRTDP1EGFR
SCHEMBL11613709 0.79 CYP3A4 (0.56) GFERCYP3A4TSHRTDP1EGFR
SCHEMBL15758556 0.78 ALOX5 (0.46) CYP3A4TSHRTDP1ALOX5PTGS2
SCHEMBL5138127 0.78 PTGS2 (0.53) CYP3A4EGFRALOX5PTGS2ALDH1A1
SCHEMBL4136744 0.78 CYP3A4 (0.54) GFERCYP3A4TSHRTDP1GABRA1
SCHEMBL27919070 0.78 CYP3A4 (0.54) GFERCYP3A4TSHRTDP1GABRA1
SCHEMBL15758094 0.78 ALOX5 (0.71) TSHRALOX5PTGS2MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116283507-A Preparation method of 2-substituted-4, 6-dibromophenol 山东京博石油化工有限公司 2023-06-23 CN disclosed