Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TYR | P14679 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8400495 | 1.00 | ALOX5 (0.53) | ALOX5PTGS2GFERCYP3A4TSHR | |
| SCHEMBL29038541 | 0.93 | GFER (0.50) | ALOX5PTGS2GFERCYP3A4TSHR | |
| SCHEMBL5138127 | 0.82 | PTGS2 (0.53) | ALOX5PTGS2CYP3A4TP53HTT | |
| SCHEMBL8400526 | 0.82 | PTGS2 (0.49) | ALOX5PTGS2CYP3A4TSHRTDP1 | |
| SCHEMBL15758556 | 0.82 | ALOX5 (0.46) | ALOX5PTGS2CYP3A4TSHRTDP1 | |
| SCHEMBL8401944 | 0.82 | PTGS2 (0.49) | ALOX5PTGS2CYP3A4TSHRTDP1 | |
| SCHEMBL15758094 | 0.81 | ALOX5 (0.71) | ALOX5PTGS2TSHRMAPT | |
| SCHEMBL28036540 | 0.79 | ALOX5 (0.44) | ALOX5PTGS2CYP3A4TSHRTDP1 | |
| SCHEMBL8398625 | 0.77 | ESR1 (0.48) | ALOX5PTGS2CYP3A4TSHRTDP1 | |
| SCHEMBL8402861 | 0.77 | ALOX5 (0.44) | ALOX5PTGS2CYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994844-B1 | HIGH INDEX OF REFRACTION MONOMERS | MINNESOTA MINING & MFG (US) | 2002-07-31 | — | — | EP | disclosed |
| EP-0994844-A1 | HIGH INDEX OF REFRACTION MONOMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-04-26 | — | — | EP | disclosed |
| WO-1998050340-A1 | HIGH INDEX OF REFRACTION MONOMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-11-12 | — | — | WO | disclosed |