Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 2/20 | 0.53 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2902181 | 1.00 | SLC1A2 (0.53) | SLC1A2SLC1A1SLC1A3FOLH1BLM | |
| SCHEMBL1197558 | 0.98 | SLC1A2 (0.50) | SLC1A2SLC1A1SLC1A3FOLH1BLM | |
| SCHEMBL5710630 | 0.98 | SLC1A2 (0.55) | SLC1A2SLC1A1SLC1A3FOLH1BLM | |
| SCHEMBL2211471 | 0.95 | FOLH1 (0.50) | SLC1A2SLC1A1SLC1A3FOLH1BLM | |
| SCHEMBL19118487 | 0.95 | FOLH1 (0.50) | SLC1A2SLC1A1SLC1A3FOLH1BLM | |
| SCHEMBL1035498 | 0.95 | FOLH1 (0.50) | SLC1A2SLC1A1SLC1A3FOLH1BLM | |
| SCHEMBL158479 | 0.95 | FOLH1 (0.50) | SLC1A2SLC1A1SLC1A3FOLH1BLM | |
| SCHEMBL2212069 | 0.95 | FOLH1 (0.50) | SLC1A2SLC1A1SLC1A3FOLH1BLM | |
| SCHEMBL8880115 | 0.95 | FOLH1 (0.50) | SLC1A2SLC1A1SLC1A3FOLH1BLM | |
| SCHEMBL2896870 | 0.95 | FOLH1 (0.50) | SLC1A2SLC1A1SLC1A3FOLH1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100322877-A1 | SILICONE ELASTOMERS IN COSMETIC ESTERS | ALZO INTERNATIONAL, INC. | 2010-12-23 | — | — | US | claimed |
| EP-2211833-A2 | SILICONE ELASTOMERS IN COSMETIC ESTERS | Alzo International, Inc. (US) | 2010-08-04 | — | — | EP | claimed |
| WO-2009054931-A2 | SILICONE ELASTOMERS IN COSMETIC ESTERS | ALZO INTERNATIONAL, INC. (US) | 2009-04-30 | — | — | WO | claimed |
| WO-2015048228-A2 | IMPROVED SILICONE ELASTOMER GELS AND RELATED HYDROSILYLATION PROCESSES | ALZO INTERNATIONAL, INC. (US) | 2015-04-02 | — | — | WO | disclosed |
| WO-2012135281-A2 | SILICONE CROSSLINKED UNSATURATED HYDROCARBON BASED POLYMERS | ALZO INTERNATIONAL, INC. (US) | 2012-10-04 | — | — | WO | disclosed |
| US-20100322877-A1 | SILICONE ELASTOMERS IN COSMETIC ESTERS | ALZO INTERNATIONAL, INC. | 2010-12-23 | — | — | US | disclosed |
| EP-2211833-A2 | SILICONE ELASTOMERS IN COSMETIC ESTERS | Alzo International, Inc. (US) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009054931-A2 | SILICONE ELASTOMERS IN COSMETIC ESTERS | ALZO INTERNATIONAL, INC. (US) | 2009-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100322877-A1 | SILICONE ELASTOMERS IN COSMETIC ESTERS | CUTA, LAGE3, MMS19 | SLC1A2 4140/4885SLC1A1 3733/4885SLC1A3 3543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.