Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 2/20 | 0.41 |
| ▸ | CDK4 | P11802 | 4/20 | 0.41 |
| ▸ | CCND1 | P24385 | 4/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.38 |
| ▸ | NNMT | P40261 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31587198 | 0.78 | PIK3CA (0.42) | EP300CDK4CCND1CHRNB2CHRNB4 | |
| SCHEMBL24932139 | 0.77 | EP300 (0.45) | EP300CDK4CCND1HDAC4SYK | |
| SCHEMBL30486010 | 0.75 | EP300 (0.43) | EP300CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL29039125 | 0.75 | EP300 (0.43) | EP300CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL30486004 | 0.75 | RXRA (0.42) | EP300CDK4CCND1CHRNB2CHRNB4 | |
| SCHEMBL16840715 | 0.74 | CCND3 (0.50) | CDK4CCND1CDK6 | |
| SCHEMBL23768373 | 0.74 | LATS1 (0.40) | SYKCDK6 | |
| SCHEMBL25949333 | 0.73 | CTSC (0.42) | CDK4CCND1CHRNB2CHRNA4HCAR3 | |
| SCHEMBL12569861 | 0.73 | POLB (0.51) | CDK4CCND1TYK2JAK2CDK6 | |
| SCHEMBL20038429 | 0.73 | CHRNB2 (0.58) | CDK4CCND1CHRNB2CHRNA4CDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116462676-A | Multi-condensed ring PRMT5 inhibitor and preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2023-07-21 | — | — | CN | disclosed |