Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.50 |
| ▸ | NPC1 | O15118 | 10/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 4/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3464201 | 0.76 | TSHR (0.51) | RAB9ANPC1SMN1; SMN2TSHRPARP1 | |
| SCHEMBL19990184 | 0.76 | TSHR (0.57) | RAB9ANPC1SMN1; SMN2TSHRGRM5 | |
| SCHEMBL6700175 | 0.76 | TSHR (0.47) | RAB9ANPC1SMN1; SMN2TSHRPARP1 | |
| SCHEMBL4597102 | 0.76 | TSHR (0.47) | RAB9ANPC1SMN1; SMN2TSHRPARP1 | |
| SCHEMBL21798813 | 0.75 | DRD3 (0.49) | RAB9ANPC1SMN1; SMN2LMNAMAPT | |
| SCHEMBL21798812 | 0.75 | DRD3 (0.49) | RAB9ANPC1SMN1; SMN2LMNAMAPT | |
| SCHEMBL24741297 | 0.75 | RAB9A (0.45) | RAB9ANPC1SMN1; SMN2TSHRPARP1 | |
| Hydrochloric Acid SCHEMBL6704096 | 0.74 | TSHR (0.46) | RAB9ANPC1SMN1; SMN2TSHRPARP1 | |
| Bromide SCHEMBL6703034 | 0.74 | TSHR (0.46) | RAB9ANPC1SMN1; SMN2TSHRPARP1 | |
| Bromide SCHEMBL7317103 | 0.74 | DRD3 (0.48) | RAB9ANPC1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1884514-B1 | METHOD FOR THE RESOLUTION OF 2-AMINO-6-PROPYLAMINO-4,5,6,7-TETRAHYDROBENZOTHIAZOL AND INTERMEDIATE COMPOUNDS | CRYSTAL PHARMA SAU (ES) | 2017-04-12 | — | — | EP | disclosed |
| EP-1884514-A4 | METHOD FOR THE RESOLUTION OF 2-AMINO-6-PROPYLAMINO-4,5,6,7-TETRAHYDROBENZOTHIAZOL AND INTERMEDIATE COMPOUNDS | RAGACTIVES SL (ES) | 2010-08-04 | — | — | EP | disclosed |
| EP-1884514-A1 | METHOD FOR THE RESOLUTION OF 2-AMINO-6-PROPYLAMINO-4,5,6,7-TETRAHYDROBENZOTHIAZOL AND INTERMEDIATE COMPOUNDS | Ragactives, S.L. (ES) | 2008-02-06 | — | — | EP | disclosed |