Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 12/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 11/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | TP53 | P04637 | 7/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.47 |
| ▸ | RELA | Q04206 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2903952 | 0.76 | RAB9A (0.50) | TSHRLMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL3458553 | 0.76 | TSHR (0.51) | TSHRLMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL13278295 | 0.74 | TSHR (0.64) | TSHRLMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL24805051 | 0.73 | TSHR (0.62) | TSHRLMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL11220484 | 0.72 | TSHR (0.65) | TSHRLMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6828225 | 0.71 | TSHR (0.40) | TSHRLMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL7955024 | 0.70 | TSHR (0.67) | TSHRLMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL659214 | 0.70 | TSHR (0.71) | TSHRLMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL24026375 | 0.70 | PARP1 (0.67) | TSHRLMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL11228337 | 0.70 | TSHR (0.74) | TSHRLMNARAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010435-A2 | FUSED OXAZOLE AND THIAZOLE DERIVATIVES AS TRPMS MODULATORS | GLENMARK PHARMACEUTICAL S.A. (CH) | 2010-01-28 | — | — | WO | disclosed |