SCHEMBL29039690

SCHEMBL29039690

COC1(N)CC(N)=CC=C1c1ccc(N)cc1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.32
ALDH1A1 P00352 2/20 0.32
CYP3A4 P08684 2/20 0.32
TP53 P04637 1/20 0.32
MAPK1 P28482 1/20 0.31
APP P05067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3787796 0.81 TDP1 (0.33) TDP1ALDH1A1CYP3A4TP53MAPK1
SCHEMBL4438733 0.77 CYP3A4 (0.39) TDP1ALDH1A1CYP3A4TP53APP
SCHEMBL28684098 0.73 ALDH1A1 (0.32) TDP1ALDH1A1CYP3A4TP53
SCHEMBL2807841 0.72 CYP3A4 (0.37) TDP1ALDH1A1CYP3A4TP53MAPK1
SCHEMBL8914064 0.72 CYP3A4 (0.37) TDP1ALDH1A1CYP3A4TP53APP
SCHEMBL8086732 0.72 CYP3A4 (0.37) TDP1ALDH1A1CYP3A4TP53APP
SCHEMBL8089981 0.71 ALDH1A1 (0.33) TDP1ALDH1A1CYP3A4TP53
Biphenyl SCHEMBL28157830 0.69 CYP3A4 (0.48) TDP1ALDH1A1CYP3A4TP53
SCHEMBL298214 0.68 KIF11 (0.37) TDP1ALDH1A1CYP3A4TP53
SCHEMBL31325656 0.68 CYP19A1 (0.33) TDP1ALDH1A1CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116082169-A Preparation method of polyurethane chain extender 2-methoxy-2' -aminobenzidine 江苏康恒化工有限公司 2023-05-09 CN disclosed
CN-116082169-A Preparation method of polyurethane chain extender 2-methoxy-2' -aminobenzidine 江苏康恒化工有限公司 2023-05-09 CN disclosed