Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8914064 | 0.82 | CYP3A4 (0.37) | CYP3A4TDP1ALDH1A1TP53TAAR1 | |
| SCHEMBL8086732 | 0.78 | CYP3A4 (0.37) | CYP3A4TDP1ALDH1A1TP53TAAR1 | |
| SCHEMBL2807841 | 0.78 | CYP3A4 (0.37) | CYP3A4TDP1ALDH1A1TP53TAAR1 | |
| SCHEMBL8089981 | 0.74 | ALDH1A1 (0.33) | CYP3A4TDP1ALDH1A1TP53 | |
| SCHEMBL3787796 | 0.74 | TDP1 (0.33) | CYP3A4TDP1ALDH1A1TP53HSD17B10 | |
| SCHEMBL298214 | 0.74 | KIF11 (0.37) | CYP3A4TDP1ALDH1A1TP53 | |
| SCHEMBL5080738 | 0.72 | ALDH1A1 (0.36) | CYP3A4TDP1ALDH1A1TP53HSD17B10 | |
| SCHEMBL2767697 | 0.67 | ESR1 (0.37) | CYP3A4ALDH1A1TP53HSD17B10MEN1 | |
| SCHEMBL41543 | 0.64 | CYP3A4 (0.39) | CYP3A4TDP1ALDH1A1TP53TAAR1 | |
| Hydrochloric Acid SCHEMBL3286109 | 0.63 | CYP3A4 (0.37) | CYP3A4TDP1ALDH1A1TP53TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118620273-A | Preparation method and application of polyimide/bismuth molybdate aerogel photocatalyst | 山东钢铁股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-115073805-B | Mesoporous PI aerogel and preparation method thereof | 山东省科学院新材料研究所 | 2024-03-22 | — | — | CN | claimed |
| CN-116854982-A | TPU (thermoplastic polyurethane) reinforced polyimide aerogel and preparation method thereof | 山东省科学院新材料研究所 | 2023-10-10 | — | — | CN | claimed |
| CN-116061098-A | High-temperature-resistant high-strength grinding wheel bushing | 江苏丰锐磨料磨具有限公司 | 2023-05-05 | — | — | CN | claimed |
| CN-115073805-A | Mesoporous PI aerogel and preparation method thereof | 山东省科学院新材料研究所 | 2022-09-20 | — | — | CN | claimed |
| CN-109622043-B | PI/Ag aerogel composite photocatalytic material and preparation method and application thereof | 山东省科学院新材料研究所 | 2021-11-02 | — | — | CN | claimed |
| CN-109622043-A | A kind of PI/Ag aeroge composite photocatalyst material and its preparation method and application | 山东省科学院新材料研究所 | 2019-04-16 | — | — | CN | claimed |
| CN-108479835-A | A kind of C (N)/g-C3N4/ PI aeroge composite photoelectric catalysis materials and preparation method thereof and its application | 山东省科学院新材料研究所 | 2018-09-04 | — | — | CN | claimed |
| CN-106633168-A | Preparation method of monodisperse and large-particle-diameter polymer microspheres | 扬州倍赛德生物科技有限公司 | 2017-05-10 | — | — | CN | claimed |
| CN-118620273-A | Preparation method and application of polyimide/bismuth molybdate aerogel photocatalyst | 山东钢铁股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-115073805-B | Mesoporous PI aerogel and preparation method thereof | 山东省科学院新材料研究所 | 2024-03-22 | — | — | CN | disclosed |
| CN-116854982-A | TPU (thermoplastic polyurethane) reinforced polyimide aerogel and preparation method thereof | 山东省科学院新材料研究所 | 2023-10-10 | — | — | CN | disclosed |
| CN-116061098-A | High-temperature-resistant high-strength grinding wheel bushing | 江苏丰锐磨料磨具有限公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-115073805-A | Mesoporous PI aerogel and preparation method thereof | 山东省科学院新材料研究所 | 2022-09-20 | — | — | CN | disclosed |
| CN-107936247-A | A kind of difficulty soluble salt and polyimide aerogels composite photo-catalyst and preparation method thereof | 山东省科学院新材料研究所 | 2018-04-20 | — | — | CN | disclosed |
| CN-106633168-A | Preparation method of monodisperse and large-particle-diameter polymer microspheres | 扬州倍赛德生物科技有限公司 | 2017-05-10 | — | — | CN | disclosed |
| US-20090148834-A1 | Methods of use of alpha-methylacyl-CoA racemase in hormone refractory and metastatic prostate cancers | MILLENNIUM PHARMACEUTICALS, INC. | 2009-06-11 | — | — | US | disclosed |
| US-20060041016-A1 | Composition and method for the treatment of psoriasis | SYNPHORA AB (SE) | 2006-02-23 | — | — | US | disclosed |
| US-20020123081-A1 | Methods of use of alpha-methylacyl-CoA racemase in hormone refractory and metastatic prostate cancers | MILLENNIUM PHARMACEUTICALS, INC. | 2002-09-05 | — | — | US | disclosed |
| WO-2002027324-A2 | METHODS OF USE OF ALPHA-METHYLACYL-CoA RACEMASE IN HORMONE REFRACTORY AND METASTATIC PROSTATE CANCERS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060041016-A1 | Composition and method for the treatment of psoriasis | PTGES2, PTGS2, PTGES | CYP3A4 426/4885TDP1 2498/4885ALDH1A1 621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.