Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28501343 | 0.85 | HDAC8 (0.34) | ALDH1A1HDAC8HPGDTDP1STING1 | |
| SCHEMBL28507196 | 0.84 | NPC1 (0.37) | MTNR1AMTNR1BHPGDSMN1; SMN2TSHR | |
| SCHEMBL28510605 | 0.84 | GAA (0.39) | ALDH1A1GAATSHR | |
| SCHEMBL28955975 | 0.84 | SMN1; SMN2 (0.36) | ALDH1A1HDAC1SMN1; SMN2TDP1RXRA | |
| SCHEMBL28859014 | 0.84 | MTNR1A (0.36) | ALDH1A1MTNR1AMTNR1BHDAC8HDAC3 | |
| SCHEMBL28510612 | 0.83 | ELANE (0.38) | ALDH1A1TDP1HSD17B10STING1 | |
| SCHEMBL29039870 | 0.82 | NOD2 (0.38) | ALDH1A1HDAC1RXRA | |
| SCHEMBL7868847 | 0.79 | FFAR1 (0.38) | SMN1; SMN2 | |
| SCHEMBL28859017 | 0.77 | ACACB (0.37) | ALDH1A1HPGDSMN1; SMN2GAAKDM4E | |
| SCHEMBL13250321 | 0.77 | CYP4F2 (0.49) | ALDH1A1MTNR1AMTNR1BPLK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116621745-A | (2-phenoxyphenyl) phenyl thioether compound and synthesis method thereof | 华北水利水电大学 | 2023-08-22 | — | — | CN | disclosed |
| CN-116496136-A | Diaryl sulfone compound and preparation method thereof | 华北水利水电大学 | 2023-07-28 | — | — | CN | disclosed |