Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | HNF4A | P41235 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28859014 | 0.88 | MTNR1A (0.36) | NPC1HTTRAB9A | |
| SCHEMBL28501343 | 0.81 | HDAC8 (0.34) | NPC1RAB9A | |
| SCHEMBL7862197 | 0.81 | FFAR1 (0.54) | FFAR1FFAR4HNF4A | |
| SCHEMBL8130559 | 0.80 | TSHR (0.43) | FFAR1NPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL28510605 | 0.80 | GAA (0.39) | — | |
| SCHEMBL28955975 | 0.80 | SMN1; SMN2 (0.36) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28507196 | 0.80 | NPC1 (0.37) | NPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL28510612 | 0.79 | ELANE (0.38) | HTT | |
| SCHEMBL29039867 | 0.79 | ALDH1A1 (0.34) | SMN1; SMN2 | |
| SCHEMBL7874063 | 0.78 | NPC1 (0.45) | NPC1HTTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300514-B1 | INHIBITING MATRIX METALLOPROTEINASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | disclosed |