Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | STK39 | Q9UEW8 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2563868 | 0.83 | POLB (0.57) | KMOPOLBAKR1C3STK39HDAC1 | |
| SCHEMBL28094815 | 0.81 | PARP10 (0.56) | KMOPOLBAKR1C3STK39HDAC1 | |
| SCHEMBL30513967 | 0.79 | TYK2 (0.51) | POLBNPC1ALDH1A1RAB9A | |
| SCHEMBL21668146 | 0.79 | TYK2 (0.51) | POLBNPC1ALDH1A1RAB9A | |
| SCHEMBL2771192 | 0.76 | MAPT (0.44) | KMOSTK39HDAC1NPC1ALDH1A1 | |
| SCHEMBL10455040 | 0.76 | ALDH1A1 (0.61) | KMOPOLBADRB1ADRB3NPC1 | |
| SCHEMBL9807211 | 0.74 | ALDH1A1 (0.65) | POLBAKR1C3PARP10SRD5A2NPC1 | |
| SCHEMBL28039268 | 0.74 | PARP10 (0.56) | KMOPOLBAKR1C3STK39PARP10 | |
| SCHEMBL596448 | 0.74 | SERPINE1 (0.58) | POLBSTK39SRD5A2SERPINE1ALDH1A1 | |
| SCHEMBL197240 | 0.74 | SERPINE1 (0.58) | POLBSTK39SRD5A2SERPINE1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116496151-A | Method for preparing fluorenone derivative by using Catellani strategy | 长沙医学院 | 2023-07-28 | — | — | CN | disclosed |